[HTML][HTML] Epigenetic pathways in human disease: the impact of DNA methylation on stress-related pathogenesis and current challenges in biomarker development

MA Argentieri, S Nagarajan, B Seddighzadeh… - …, 2017 - thelancet.com
… , is to critically examine the extant literature on DNA methylation of CRH, CRH-R1/2, CRH-…
need to be addressed in order to develop clinically meaningful prognostic biomarkers, and to …

Genetic alterations of DNA methylation machinery in human diseases

T Hamidi, AK Singh, T Chen - Epigenomics, 2015 - Taylor & Francis
… Genetic studies in mice demonstrate that DNA methylation is essential for mammalian
development and plays crucial roles in numerous biological processes, including genomic …

[图书][B] DNA methylation and complex human disease

M Neidhart - 2015 - books.google.com
… to develop a disease, screen for early detection of disease, … DNA methylation in the
pathogenesis of various diseases has coincided with advances in platform-based DNA methylation

DNA methylation in health, disease, and cancer

DS Shames, JD Minna… - Current molecular …, 2007 - ingentaconnect.com
hypermethylation. Here we review recent findings on altered DNA methylation in human
disease, … of this review involves DNA methylation and its role in cancer development. However, …

DNA methylation in early development

TM Geiman, K Muegge - … Reproduction and Development …, 2010 - Wiley Online Library
… Epigenetic alterations such as DNA methylation are an … at the role of DNA methylation in
early embryonic development, as … DNA methylation modifier which leads to human disease if mu…

Research progress in predicting DNA methylation modifications and the relation with human diseases

C Ao, L Gao, L Yu - Current Medicinal Chemistry, 2022 - ingentaconnect.com
DNA methylation modification sites are helpful for the development of biological functions. …
experimental techniques have been developed for DNA methylation detection, including high-…

[HTML][HTML] DNA methylation and DNA methyltransferases

JR Edwards, O Yarychkivska, M Boulard… - Epigenetics & …, 2017 - Springer
development. We observe that the sequences that undergo deep changes in methylation
status during early development are … We also describe the several human disorders, each very …

[HTML][HTML] Genome-wide analysis of DNA methylation dynamics during early human development

H Okae, H Chiba, H Hiura, H Hamada, A Sato… - PLoS …, 2014 - journals.plos.org
DNA methyltransferases. These data highlight both conserved and species-specific regulation
of DNA methylation during early mammalian development. … early human development. …

[HTML][HTML] Mitochondrial DNA methylation and human diseases

A Stoccoro, F Coppedè - International Journal of Molecular Sciences, 2021 - mdpi.com
… with obesity develop CVDs while others remain disease-free, methylation levels of several …
whom 84 developed cardiovascular disease [83]. The authors found that methylation levels of …

[HTML][HTML] DNA methylation in development and disease: an overview for prostate researchers

DB Joseph, DW Strand, CM Vezina - American journal of clinical …, 2018 - ncbi.nlm.nih.gov
… susceptibility to disease or trigger processes that lead to disease. In … DNA methylation
machinery. More specifically, we describe DNA methylation in the context of prostate development, …