[HTML][HTML] Epigenetic pathways in human disease: the impact of DNA methylation on stress-related pathogenesis and current challenges in biomarker development
MA Argentieri, S Nagarajan, B Seddighzadeh… - …, 2017 - thelancet.com
… , is to critically examine the extant literature on DNA methylation of CRH, CRH-R1/2, CRH-…
need to be addressed in order to develop clinically meaningful prognostic biomarkers, and to …
need to be addressed in order to develop clinically meaningful prognostic biomarkers, and to …
Genetic alterations of DNA methylation machinery in human diseases
T Hamidi, AK Singh, T Chen - Epigenomics, 2015 - Taylor & Francis
… Genetic studies in mice demonstrate that DNA methylation is essential for mammalian
development and plays crucial roles in numerous biological processes, including genomic …
development and plays crucial roles in numerous biological processes, including genomic …
[图书][B] DNA methylation and complex human disease
M Neidhart - 2015 - books.google.com
… to develop a disease, screen for early detection of disease, … DNA methylation in the
pathogenesis of various diseases has coincided with advances in platform-based DNA methylation …
pathogenesis of various diseases has coincided with advances in platform-based DNA methylation …
DNA methylation in health, disease, and cancer
DS Shames, JD Minna… - Current molecular …, 2007 - ingentaconnect.com
… hypermethylation. Here we review recent findings on altered DNA methylation in human
disease, … of this review involves DNA methylation and its role in cancer development. However, …
disease, … of this review involves DNA methylation and its role in cancer development. However, …
DNA methylation in early development
TM Geiman, K Muegge - … Reproduction and Development …, 2010 - Wiley Online Library
… Epigenetic alterations such as DNA methylation are an … at the role of DNA methylation in
early embryonic development, as … DNA methylation modifier which leads to human disease if mu…
early embryonic development, as … DNA methylation modifier which leads to human disease if mu…
Research progress in predicting DNA methylation modifications and the relation with human diseases
C Ao, L Gao, L Yu - Current Medicinal Chemistry, 2022 - ingentaconnect.com
… DNA methylation modification sites are helpful for the development of biological functions. …
experimental techniques have been developed for DNA methylation detection, including high-…
experimental techniques have been developed for DNA methylation detection, including high-…
[HTML][HTML] DNA methylation and DNA methyltransferases
JR Edwards, O Yarychkivska, M Boulard… - Epigenetics & …, 2017 - Springer
… development. We observe that the sequences that undergo deep changes in methylation
status during early development are … We also describe the several human disorders, each very …
status during early development are … We also describe the several human disorders, each very …
[HTML][HTML] Genome-wide analysis of DNA methylation dynamics during early human development
H Okae, H Chiba, H Hiura, H Hamada, A Sato… - PLoS …, 2014 - journals.plos.org
… DNA methyltransferases. These data highlight both conserved and species-specific regulation
of DNA methylation during early mammalian development. … early human development. …
of DNA methylation during early mammalian development. … early human development. …
[HTML][HTML] Mitochondrial DNA methylation and human diseases
A Stoccoro, F Coppedè - International Journal of Molecular Sciences, 2021 - mdpi.com
… with obesity develop CVDs while others remain disease-free, methylation levels of several …
whom 84 developed cardiovascular disease [83]. The authors found that methylation levels of …
whom 84 developed cardiovascular disease [83]. The authors found that methylation levels of …
[HTML][HTML] DNA methylation in development and disease: an overview for prostate researchers
… susceptibility to disease or trigger processes that lead to disease. In … DNA methylation
machinery. More specifically, we describe DNA methylation in the context of prostate development, …
machinery. More specifically, we describe DNA methylation in the context of prostate development, …