… DNA methylation can result in human diseases such as imprinting disorders and cancer. …
basic concepts of DNA methylation and its relevance to normal development and regulation of …

… the importance of epigenetic changes in development and disease. The methods described
… and monitoring of disease-associated changes in the DNA methylation patterns. This …

… Because of the usefulness of reference methylation maps in human DNA methylation analysis,
we … We will develop new data processing algorithms to handle the large-scale nature of …

… Mitotic transmission of these states implies that the DNA methylation patterns are copied
onto … The DNA methylation patterns are replicated by the maintenance DNA methyltransferase …

… of DNA methylation in silencing the transcription of key tumor suppressor genes and thus
promoting the development … changes working in concert with DNA methylation affect either the …

… in human DNA methylation patterns are an important feature of cancer development and …
other conditions such as atherosclerosis and autoimmune diseases (eg, multiple sclerosis and …

… Studies are also beginning to integrate brain imaging data to investigate the links between
DNA methylation, brain development and neuropsychiatric outcomes. For example, a recent …

… DNA methyltransferases and from rodents or humans with somatically acquired changes in
DNA methylation that illustrate the disease-… development by differential DNA methylation. …

… on placental DNA methylation … fetal development and disease susceptibility. Prenatal
exposure to air pollution and heavy metals was associated with altered placental DNA methylation …

… regulatory effects of both hypo- and hyper-DNA methylation on cancer. In this review, we …
DNA methylation on cancer development. Indeed, alteration of the pattern of DNA methylation …