DNA Methylation plays important roles in retinal development and diseases

J Wu, L Liu, M Cao, A Hu, D Hu, Y Luo, H Wang… - Experimental Eye …, 2021 - Elsevier
… and shows potential in disease diagnoses and prognoses. … of DNA methylation and
demethylation with an emphasis on their regulatory roles in retinal development and related diseases

DNA methylation abnormalities in congenital heart disease

C Serra-Juhé, I Cuscó, A Homs, R Flores, N Torán… - Epigenetics, 2015 - Taylor & Francis
DNA methylation through its transcriptional consequences may have an important role in
human disease… epimutations altering DNA methylation in fetal heart cells to the development of …

Do age-related changes in DNA methylation play a role in the development of age-related diseases?

SD van Otterdijk, JC Mathers… - Biochemical Society …, 2013 - portlandpress.com
methylation are observed in diseases An important role for altered DNA methylation in the
development of disease is strongly suggested by the growing number of human diseases that …

DNA methylation-based variation between human populations

F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
… It is an epigenetic mark of paramount importance for normal development in the human
genome. The role of DNA methylation in differential regulation of gene expression, imprinting (…

DNA hypermethylation in disease: mechanisms and clinical relevance

M Ehrlich - Epigenetics, 2019 - Taylor & Francis
… is also associated with neurological diseases, immunological diseases, atherosclerosis, …
discuss DNA hypermethylation in disease and its interrelationships with normal development as …

DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging

K Kim, S Friso, SW Choi - The Journal of nutritional biochemistry, 2009 - Elsevier
… However, established DNA methylation patterns are not immutable and can be modified … in
DNA methylation with diet may lead to the development of age-associated diseases including …

Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans

DJ Martino, MK Tulic, L Gordon, M Hodder… - Epigenetics, 2011 - Taylor & Francis
… in immune related disorders known to develop prior to this age had been confirmed. Whilst
the primary aim of this paper was to investigate temporal changes in DNA methylation, the …

Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex

KA Perzel Mandell, AJ Price, R Wilton… - Epigenetics, 2021 - Taylor & Francis
disease development, we must first understand the normal landscape. Illuminating typical
methylation changes in prenatal development … active in the postnatal developing brain, and …

Genetics meets DNA methylation in rare diseases

G Velasco, C Francastel - Clinical genetics, 2019 - Wiley Online Library
disorders of epigenetic machineries. These discoveries contribute both to advancing our
understanding of the etiology of a number of human diseases,3 … in organismal development. …

Understanding the relevance of DNA methylation changes in immune differentiation and disease

C Calle-Fabregat, O Morante-Palacios, E Ballestar - Genes, 2020 - mdpi.com
… play a role in human diseases by their ability to … DNA methylation in health and disease.
This review considers the relevance of DNA methylation to immune system cellular development