DNA Methylation plays important roles in retinal development and diseases
J Wu, L Liu, M Cao, A Hu, D Hu, Y Luo, H Wang… - Experimental Eye …, 2021 - Elsevier
… and shows potential in disease diagnoses and prognoses. … of DNA methylation and
demethylation with an emphasis on their regulatory roles in retinal development and related diseases…
demethylation with an emphasis on their regulatory roles in retinal development and related diseases…
DNA methylation abnormalities in congenital heart disease
C Serra-Juhé, I Cuscó, A Homs, R Flores, N Torán… - Epigenetics, 2015 - Taylor & Francis
… DNA methylation through its transcriptional consequences may have an important role in
human disease… epimutations altering DNA methylation in fetal heart cells to the development of …
human disease… epimutations altering DNA methylation in fetal heart cells to the development of …
Do age-related changes in DNA methylation play a role in the development of age-related diseases?
SD van Otterdijk, JC Mathers… - Biochemical Society …, 2013 - portlandpress.com
… methylation are observed in diseases An important role for altered DNA methylation in the
development of disease is strongly suggested by the growing number of human diseases that …
development of disease is strongly suggested by the growing number of human diseases that …
DNA methylation-based variation between human populations
F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
… It is an epigenetic mark of paramount importance for normal development in the human
genome. The role of DNA methylation in differential regulation of gene expression, imprinting (…
genome. The role of DNA methylation in differential regulation of gene expression, imprinting (…
DNA hypermethylation in disease: mechanisms and clinical relevance
M Ehrlich - Epigenetics, 2019 - Taylor & Francis
… is also associated with neurological diseases, immunological diseases, atherosclerosis, …
discuss DNA hypermethylation in disease and its interrelationships with normal development as …
discuss DNA hypermethylation in disease and its interrelationships with normal development as …
DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging
… However, established DNA methylation patterns are not immutable and can be modified … in
DNA methylation with diet may lead to the development of age-associated diseases including …
DNA methylation with diet may lead to the development of age-associated diseases including …
Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans
… in immune related disorders known to develop prior to this age had been confirmed. Whilst
the primary aim of this paper was to investigate temporal changes in DNA methylation, the …
the primary aim of this paper was to investigate temporal changes in DNA methylation, the …
Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex
KA Perzel Mandell, AJ Price, R Wilton… - Epigenetics, 2021 - Taylor & Francis
… disease development, we must first understand the normal landscape. Illuminating typical
methylation changes in prenatal development … active in the postnatal developing brain, and …
methylation changes in prenatal development … active in the postnatal developing brain, and …
Genetics meets DNA methylation in rare diseases
G Velasco, C Francastel - Clinical genetics, 2019 - Wiley Online Library
… disorders of epigenetic machineries. These discoveries contribute both to advancing our
understanding of the etiology of a number of human diseases,3 … in organismal development. …
understanding of the etiology of a number of human diseases,3 … in organismal development. …
Understanding the relevance of DNA methylation changes in immune differentiation and disease
… play a role in human diseases by their ability to … DNA methylation in health and disease.
This review considers the relevance of DNA methylation to immune system cellular development …
This review considers the relevance of DNA methylation to immune system cellular development …