DNA methylation in genes associated with the evolution of ageing and disease: A critical review

MT Mc Auley - Ageing Research Reviews, 2021 - Elsevier
… /development theory, and like … developing breast/ovarian cancer (Smith et al., 2013).
Cognisant of these caveats the next section will examine recent evidence for AP in human disease. …

Stability and lability of parental methylation imprints in development and disease

S Farhadova, M Gomez-Velazquez, R Feil - Genes, 2019 - mdpi.com
DNA methylation and histone methylation imprints, their somatic maintenance during
development… may become perturbed in concert in human disease contexts. Recent data provide …

Social and physical environments early in development predict DNA methylation of inflammatory genes in young adulthood

TW McDade, C Ryan, MJ Jones… - Proceedings of the …, 2017 - National Acad Sciences
… Chronic inflammation contributes to a wide range of human diseases, and environments in
… We tested the hypothesis that patterns of DNA methylation (DNAm) in inflammatory genes in …

Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation

AJ Price, L Collado-Torres, NA Ivanov, W Xia, EE Burke… - Genome biology, 2019 - Springer
… across prenatal and postnatal human brain development, we show that the first … methylation
(mCpG and mCpH, respectively) and gene expression and splicing in neuronal development

Impact of aging on DNA methylation

B Richardson - Ageing research reviews, 2003 - Elsevier
… status of specific genes with aging, their impact on diseases that develop with aging, and
mechanisms … Mutations in the DNA methylation machinery also contribute to human diseases. …

Genome‐wide analysis of DNA methylation in relation to socioeconomic status during development and early adulthood

TW McDade, CP Ryan, MJ Jones… - American journal of …, 2019 - Wiley Online Library
… This study investigates whether levels of DNA methylation at CpG sites across the genome
… profiles of DNA methylation in young adulthood are predicted by SES early in development (…

The prima donna of epigenetics: the regulation of gene expression by DNA methylation

KF Santos, TN Mazzola, HF Carvalho - Brazilian Journal of Medical …, 2005 - SciELO Brasil
… mechanisms of DNA methylation, DNA methylation pattern … of DNA methylation with
imprinting, embryonic development … , and DNA methylation in particular, in human diseases has …

Two approaches reveal a new paradigm of 'switchable or genetics-influenced allele-specific DNA methylation'with potential in human disease

SN Martos, T Li, RB Ramos, D Lou, H Dai, JC Xu… - Cell discovery, 2017 - nature.com
… We further developed an algorithm based on a genetic variation-independent approach (…
and/or have bimodal methylation patterns. We begin with examining DNA methylation patterns …

Evolution of DNA methylation in the human brain

H Jeong, I Mendizabal, S Berto, P Chatterjee… - Nature …, 2021 - nature.com
… in development, learning, memory, and disease in the human brain. Here we have elucidated
DNA methylation changes during recent human … , we applied methods developed for the …

Folate and DNA methylation during in utero development and aging

JA McKay, EA Williams… - Biochemical Society …, 2004 - portlandpress.com
… , the impact of folic acid availability in utero on DNA methylation patterns and disease risk …
DNA methylation, and the association between DNA methylation during in utero development