Toxicological effects of benzo [a] pyrene on DNA methylation of whole genome in ICR mice
L Zhao, S Zhang, X An, W Tan, D Pang… - Cellular and molecular …, 2015 - cellmolbiol.org
… in DNA methylation of whole genome due to benzo[a] pyrene exposure. In this study, the
effects of benzo[a] pyrene on DNA methylation … of benzo[a]pyrene to ICR mice. The toxicity and …
effects of benzo[a] pyrene on DNA methylation … of benzo[a]pyrene to ICR mice. The toxicity and …
Dynamic changes of DNA methylation induced by benzo (a) pyrene in cancer
H Wang, B Liu, H Chen, P Xu, H Xue, J Yuan - Genes and Environment, 2023 - Springer
… Similarly, when BaP was administrated at a dose of 600 mg/kg to the male ICR mice, the
genome-wide DNA methylation level in blood and liver followed a downward trend along with …
genome-wide DNA methylation level in blood and liver followed a downward trend along with …
Influence of benzo (a) pyrene on different epigenetic processes
B Bukowska, P Sicińska - International Journal of Molecular Sciences, 2021 - mdpi.com
… in the whole genomic DNA methylation of the Institute of Cancer Research (ICR) mice
exposed to BaP. Blood, liver, pancreas, skin, lung, and bladder of IRC mice were removed and …
exposed to BaP. Blood, liver, pancreas, skin, lung, and bladder of IRC mice were removed and …
The effect of benzo [alpha] pyrene on DNA methylation and telomerase activity in human normal and cancer cells
… BaP also non-significantly decreased global methylation levels … and DNA methylation in
human normal and cancer cells. … changes that include DNA methylation, histone modifications, …
human normal and cancer cells. … changes that include DNA methylation, histone modifications, …
Aspirin ameliorates the cognition impairment in mice following benzo [a] pyrene treatment via down-regulating BDNF IV methylation
Y Li, J Cao, Z Hao, A Liu, X Li, H Li, N Xia, Z Wang… - Neurotoxicology, 2022 - Elsevier
… DNA methylation, as well as BDNF mRNA and protein levels in the cerebral cortex in ICR
mice … This study focused on the BDNF IV DNA methylation in the cognitive impairment in mice …
mice … This study focused on the BDNF IV DNA methylation in the cognitive impairment in mice …
… and alterations of mRNA, protein, and DNA methylation of CYP1A1, GSTP1, and GSTM1 induced by benzo[a]pyrene and the intervention of aspirin in mice
A Liu, X Li, L Zhou, X Yan, N Xia, Z Song, J Cao… - … Science and Pollution …, 2023 - Springer
… Forty healthy male ICR mice at 8 weeks of age were purchased from Beijing Xingwang …
Also, we found the DNA hypermethylation of GSTP1 in the cerebrum of mice following B[a]P …
Also, we found the DNA hypermethylation of GSTP1 in the cerebrum of mice following B[a]P …
Inhibition of benzo [a] pyrene-DNA adduct formation by Aloe barbadensis Miller.
HS Kim, BM Lee - Carcinogenesis, 1997 - academic.oup.com
… –DNA After a single oral administration of B[a]P to male ICR binding by molecular complex
formation in the gut and reduced mice (10 mg/mouse), benzo[a]pyrene … and DNA methylation …
formation in the gut and reduced mice (10 mg/mouse), benzo[a]pyrene … and DNA methylation …
Benzo [a] pyrene-induced multigenerational changes in gene expression, behavior, and DNA methylation are primarily influenced by paternal exposure
Z Pandelides, MC Sturgis, C Thornton, N Aluru… - Toxicology and Applied …, 2023 - Elsevier
… exposure, we conducted transcriptome and DNA methylation profiling in F0 gametes (sperm …
suggesting regulation of chromatin conformation by DNA methylation. Overall, these results …
suggesting regulation of chromatin conformation by DNA methylation. Overall, these results …
Maternal benzo [a] pyrene exposure is correlated with the meiotic arrest and quality deterioration of offspring oocytes in mice
L Sui, J Nie, P Xiao, K Yan, H Zhang, J Liu… - Reproductive …, 2020 - Elsevier
… Research (ICR) female mice that were 4–5 … DNA methylation patterns play a pivotal role in
preimplantation development [[34], [35], [36]]. We next determined the global DNA methylation …
preimplantation development [[34], [35], [36]]. We next determined the global DNA methylation …
Carcinogenicity of 7H-dibenzo [c, g] carbazole, dibenz [a, j] acridine and benzo [a] pyrene in mouse skin and liver following topical application
D Warshawsky, W Barkley, ML Miller, K LaDow… - Toxicology, 1994 - Elsevier
… :ICR(Br) mouse which is equivalent to the CD-l mouse. A good correlation has been shown
between tumor-initiating activity of PAHs and NHA and their ability to covalently bind to DNA (…
between tumor-initiating activity of PAHs and NHA and their ability to covalently bind to DNA (…
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