Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results …
… Levels of IgG and IgM autoantibodies (AA) to malondialdehyde (MDA)-LDL and apoB-immune
complexes (ICs) were measured in 748 cases and 1,723 controls in the EPIC-Norfolk …
complexes (ICs) were measured in 748 cases and 1,723 controls in the EPIC-Norfolk …
Nature and functions of autoantibodies
K Elkon, P Casali - Nature clinical practice Rheumatology, 2008 - nature.com
… Thus, immune complexes might perpetuate a positive feedback loop amplifying … unmutated
IgM, autoantibodies differ fundamentally from those of high-affinity, somatically mutated IgG …
IgM, autoantibodies differ fundamentally from those of high-affinity, somatically mutated IgG …
Role of natural and immune IgM antibodies in immune responses
M Boes - Molecular immunology, 2000 - Elsevier
… induce deposition of activated C3 on the immune complex and formation of Ag–IgM–C′
complex. Accordingly, binding of IgM-containing immune complexes on FDC most likely occurs …
complex. Accordingly, binding of IgM-containing immune complexes on FDC most likely occurs …
Autoantibody-induced formation of immune complexes in normal human serum
R Lemieux, R Bazin - Current pharmaceutical design, 2006 - ingentaconnect.com
… IgM autoantibodies had been isolated from the serum of normal animals or humans, it was
shown that only IgM … They further showed that serum IgM were the main serum component …
shown that only IgM … They further showed that serum IgM were the main serum component …
Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice.
DA Nemazee - The Journal of experimental medicine, 1985 - europepmc.org
… that the anti-IgG response is predominantly of the IgM class and includes little or no IgG
antibody. This isotype pattern is typical of T cell-independent responses. The rheumatoid …
antibody. This isotype pattern is typical of T cell-independent responses. The rheumatoid …
Increased immune complexes of hypocretin autoantibodies in narcolepsy
A Deloumeau, S Bayard, Q Coquerel, P Déchelotte… - PLoS …, 2010 - journals.plos.org
… IgM autoantibodies and with anti-idiotypic IgM autoantibodies… Because a fraction of autoAbs
exist in immune complexes … -glycine buffer which dissociates immune complexes. With this …
exist in immune complexes … -glycine buffer which dissociates immune complexes. With this …
Natural antibody to apoptotic cell membranes inhibits the proinflammatory properties of lupus autoantibody immune complexes
J Vas, C Grönwall, A Marshak‐Rothstein… - Arthritis & …, 2012 - Wiley Online Library
… However, when the IgM anti-AC NAb antibody was later added, we were unable to detect
an association of this IgM antibody (data available upon request from the author) with the plate-…
an association of this IgM antibody (data available upon request from the author) with the plate-…
IgM rheumatoid factor amplifies the inflammatory response of macrophages induced by the rheumatoid arthritis-specific immune complexes containing anticitrullinated …
L Laurent, F Anquetil, C Clavel… - Annals of the …, 2015 - ard.bmj.com
… We showed that immune complexes containing IgG ACPA (… Since IgM rheumatoid factor
(RF), an autoantibody directed to … individuals and different human IgM cryoglobulins with RF …
(RF), an autoantibody directed to … individuals and different human IgM cryoglobulins with RF …
Warm autoimmune hemolytic anemia is an IgM–IgG immune complex disease
D Stahl, W Sibrowski - Journal of autoimmunity, 2005 - Elsevier
… In the present study, we purified and characterized IgM from plasma of WAIHA patients and
… within the IgM fractions. We provide evidence that IgM–IgG immune complexes in plasma …
… within the IgM fractions. We provide evidence that IgM–IgG immune complexes in plasma …
Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM
M Boes, T Schmidt, K Linkemann… - Proceedings of the …, 2000 - National Acad Sciences
… IgG antibody responses to foreign antigens, probably through formation of immune complexes
of antigen, IgM… The resulting immune complexes are more effective in activating B cells by …
of antigen, IgM… The resulting immune complexes are more effective in activating B cells by …