… This randomized phase III study evaluated the efficacy and safety of the novel topoisomerase
… not met and thus this randomized phase III trial should be regarded as a negative study. …

… A pivotal phase III study 1 demonstrated that the addition of … We had initially begun a
randomized phase III trial, designated … After the pivotal phase III data for bevacizumab became …

… -GC) is a randomized phase III trial to confirm the effectiveness of 1-year postoperative
treatment with S-1 compared with surgery alone in patients with stage II or III gastric cancer who …

… We conducted a prospective randomized study of IV induction therapy versus a full year of
high-dose IFN, with primary end points of RFS and OS for patients with stage IIB, IIC, and III …

… objective of this randomized phase II/phase III study was to investigate the efhcacy and toxicity
of equimolar doses of adriamycin (ADM) and 4-epiadriamycin (EPI) in patients with locally …

… Capecitabine remains the adjuvant standard of care after curatively resected BTC and the
control arm of future randomized studies. The BILCAP study was a randomized phase III study …

… Therefore, this phase III study, in conjunction with a separate phase III study of lower daily
doses, 5 provides support for the clinical utility of targeting AMPA receptors for the treatment of …

… There had been no prospective phase III studies directly … a multicenter randomized phase III
study to demonstrate the … the first prospective randomized phase III study to directly compare …

… This is the largest ever and the only published randomized phase III study on this rare … the
results of the ITT analysis of randomized study arms, which further supports the validity of the …

Purpose We conducted a phase III trial to determine whether first-line treatment with raltitrexed,
a thymidine synthase inhibitor, and cisplatin results in superior outcome compared with …