[HTML][HTML] Structural biology of SARS-CoV-2 and implications for therapeutic development
H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
… SARS-CoV-2 proteins can … of SARS-CoV-2 from the whole viral particle to the individual
viral proteins and discuss their functions as well as their potential as targets for therapeutic …
viral proteins and discuss their functions as well as their potential as targets for therapeutic …
[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
… syndrome coronavirus 2 (SARS‐CoV‐2) by the coronavirus … caused by the 2019‐nCoV as
coronavirus disease (COVID‐19)… Therefore, we will review the current therapeutic and vaccine …
coronavirus disease (COVID‐19)… Therefore, we will review the current therapeutic and vaccine …
Modelling SARS-CoV-2 dynamics: implications for therapy
… into optimal usage of anti-SARS-CoV-2 therapies under development. In particular, it … -SARS-CoV-2
therapies to investigate the expected outcome under hypothetical drug therapies (or …
therapies to investigate the expected outcome under hypothetical drug therapies (or …
[HTML][HTML] SARS-CoV-2 infection: symptoms of the nervous system and implications for therapy in neurological disorders
J Losy - Neurology and therapy, 2021 - Springer
In this paper, the neurological aspects of COVID-19 are presented, which may be of
significance for physicians. Knowledge about the neurological symptoms of COVID-19 infection …
significance for physicians. Knowledge about the neurological symptoms of COVID-19 infection …
SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19
… SARS-CoV-2, similar to SARS-CoV, has characteristic transmembrane trimeric proteins that
facilitate the binding and fusion of the viral particle to the surface of the cell membrane of the …
facilitate the binding and fusion of the viral particle to the surface of the cell membrane of the …
[HTML][HTML] Interactions of influenza and SARS-CoV-2 with the lung endothelium: similarities, differences, and implications for therapy
E Latreille, WL Lee - Viruses, 2021 - mdpi.com
… as influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are a
constant … In this review, we discuss how infection with influenza or SARS-CoV-2 may induce …
constant … In this review, we discuss how infection with influenza or SARS-CoV-2 may induce …
[HTML][HTML] Implications of sex differences in immunity for SARS-CoV-2 pathogenesis and design of therapeutic interventions
MJ Bunders, M Altfeld - Immunity, 2020 - cell.com
… with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are insufficiently …
on SARS-CoV-2 pathogenesis and pathology to identify targets for therapeutic interventions …
on SARS-CoV-2 pathogenesis and pathology to identify targets for therapeutic interventions …
Interaction of SARS-CoV-2 and other coronavirus with ACE (angiotensin-converting enzyme)-2 as their main receptor: therapeutic implications
AM Davidson, J Wysocki, D Batlle - Hypertension, 2020 - Am Heart Assoc
… and infectivity by SARS-CoV. From this information, we also discuss potential therapeutic
opportunities including the use of soluble ACE2 proteins to intercept the SARS-CoV-2 so that …
opportunities including the use of soluble ACE2 proteins to intercept the SARS-CoV-2 so that …
Clinical phenotypes of SARS-CoV-2: implications for clinicians and researchers
J Rello, E Storti, M Belliato… - European Respiratory …, 2020 - Eur Respiratory Soc
… This article reports clinical experience from the SARS-CoV-2 … As with influenza, reverse
transcriptase-PCR for SARS-CoV-2 is … In China, SARS-CoV-2 has not shown a more severe …
transcriptase-PCR for SARS-CoV-2 is … In China, SARS-CoV-2 has not shown a more severe …
The thrilling journey of SARS-CoV-2 into the intestine: from pathogenesis to future clinical implications
… In this review, we focus on the current evidence of the relationship between SARS-CoV-2
and the gastrointestinal system; we outline the main implications on the management of …
and the gastrointestinal system; we outline the main implications on the management of …