DNA methylation analysis by pyrosequencing

J Tost, IG Gut - Nature protocols, 2007 - nature.com
importance for DNA methylation analysis in various developmental and pathological situations.
Analysis of DNA methylation … measures of the degree of methylation at several CpGs in …

[PDF][PDF] Epigenetic patterning in male germ cells: importance of DNA methylation to progeny outcome

S La Salle, JM Trasler, C De Jonge… - The sperm cell …, 2006 - academia.edu
DNA methylation, one of the best-characterized DNA modifications associated with the
modulation of gene activity. In humans, DNA methylation … -wide epigenetic methylation patterns …

DNA methylation properties: consequences for pharmacology

M Szyf - Trends in pharmacological sciences, 1994 - cell.com
… One candidate that may play an important role is DNA methylationmethylation patterns
suggests that DNA methylation patterns are inherited during replication. This is because the DNA

How does DNA methylation repress transcription?

SU Kass, D Pruss, AP Wolffe - Trends in Genetics, 1997 - cell.com
… The importance of DNA methylation and methylationspecific DNA-binding proteins for the …
An attractive explanation for the importance of DNA methylation is that it helps to turn off …

Expression of various genes is controlled by DNA methylation during mammalian development

M Ehrlich - Journal of cellular biochemistry, 2003 - Wiley Online Library
… alter the catalytic domain of DNMT3B indicates that normal levels of DNA methylation in
humans are important for regulating expression of certain genes involved in differentiation. …

DNA methylation in development and human disease

S Gopalakrishnan, BO Van Emburgh… - … Molecular Mechanisms of …, 2008 - Elsevier
… Inactivation of Lsh also leads to loss of PRC1 and PRC2-associated chromatin marks,
suggesting that Lsh and DNA methylation are important for complete assembly and activity of the …

DNA methylation 40 years later: Its role in human health and disease

MI Scarano, M Strazzullo, MR Matarazzo… - Journal of cellular …, 2005 - Wiley Online Library
DNA methylation has long been thought to be an important component of X chromosome
inactivation, particularly as a mechanism for stably maintaining the inactive state of X-linked …

DNA methylation, imprinting and cancer

C Plass, PD Soloway - European Journal of Human Genetics, 2002 - nature.com
… The importance of each of these enzymes for normal development has been demonstrated
… These experiments dramatically revealed the importance of DNA methylation in normal …

The evolving functions of DNA methylation

D Zilberman - Current opinion in plant biology, 2008 - Elsevier
… of either strand is sufficient for protection from cleavage, a property that is particularly
important during DNA replication [2]. Symmetry ensures that the sites generated by …

Principles of DNA methylation and their implications for biology and medicine

Y Dor, H Cedar - The Lancet, 2018 - thelancet.com
… In this Review we provide a map of the DNA methylation landscape, … We also discuss how
DNA methylation could provide a … This important principle could also help with understanding …