DNA methylation in mammals
E Li, Y Zhang - Cold Spring Harbor perspectives in …, 2014 - cshperspectives.cshlp.org
… This is addressed in this section, as well as describing important work mapping the
distribution and methylation patterns of CpG sequences in the mammalian genome and their …
distribution and methylation patterns of CpG sequences in the mammalian genome and their …
Methods in DNA methylation profiling
… Metastable and somatically heritable patterns of DNA methylation provide an important …
important discoveries will continue to be made using genome-wide DNA methylation profiling. …
important discoveries will continue to be made using genome-wide DNA methylation profiling. …
[HTML][HTML] DNA methylation in the pathogenesis of type 2 diabetes in humans
… focus on alterations in DNA methylation in four human tissues of importance for the disease;
… -genetic and genetic risk factors on DNA methylation in humans will be considered. These …
… -genetic and genetic risk factors on DNA methylation in humans will be considered. These …
Notes on the role of dynamic DNA methylation in mammalian development
TH Bestor, JR Edwards… - Proceedings of the …, 2015 - National Acad Sciences
… and represses genes via reversible DNA methylation. Such a … DNA methylation does have
essential roles in irreversible … either methylated or unmethylated genomes, DNA methylation …
essential roles in irreversible … either methylated or unmethylated genomes, DNA methylation …
The role of DNA methylation in cancer genetics and epigenetics
PW Laird, R Jaenisch - Annual review of genetics, 1996 - annualreviews.org
… The second important advance has been the demonstration … by DNA methylation. The
thirddevelopment has been the utilization of experimental methods to manipulate DNAmethylation …
thirddevelopment has been the utilization of experimental methods to manipulate DNAmethylation …
Dynamics and function of DNA methylation in plants
… We also discuss the important roles of DNA methylation dynamics in regulating transposon
silencing, in gene expression, in chromosome interactions, in plant development and in plant …
silencing, in gene expression, in chromosome interactions, in plant development and in plant …
DNA methylation and healthy human aging
… an important component of the aging process. The epigenetic mark that has been most highly
studied is DNA methylation, … Early studies indicated that global levels of DNA methylation …
studied is DNA methylation, … Early studies indicated that global levels of DNA methylation …
[HTML][HTML] DNA methylation: a timeline of methods and applications
A Harrison, A Parle-McDermott - Frontiers in genetics, 2011 - frontiersin.org
… An epigenetic modification associated with gene regulation, DNA methylation is of paramount
importance to biological health and disease. Recently, the quest to unravel the Human …
importance to biological health and disease. Recently, the quest to unravel the Human …
Function and information content of DNA methylation
D Schübeler - Nature, 2015 - nature.com
… and function of DNA methylation in mammals, and discusses the utility of DNA methylation as
a … This important aspect of DNA methylation biology is not the focus of this Review and has …
a … This important aspect of DNA methylation biology is not the focus of this Review and has …
DNA methylation and apoptosis
G Gopisetty, K Ramachandran, R Singal - Molecular immunology, 2006 - Elsevier
… Studies from various cancers have revealed that DNA methylation affects genes involved in
… important factor aiding its evolution. Evidence from literature indicates that DNA methylation …
… important factor aiding its evolution. Evidence from literature indicates that DNA methylation …