Functions of DNA methylation: islands, start sites, gene bodies and beyond

PA Jones - Nature reviews genetics, 2012 - nature.com
… of a CTCF-binding site at this locus blocks the binding of CTCF, so DNA methylation has
an important role in controlling this locus 79 . More recent studies have likewise shown that …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
DNA methylation is of paramount importance for mammalian … DNA methylation in embryonic,
germline and somatic cell development. Finally, we provide insights into DNA methylation

DNA methylation in development and human disease

S Gopalakrishnan, BO Van Emburgh… - … Molecular Mechanisms of …, 2008 - Elsevier
… Inactivation of Lsh also leads to loss of PRC1 and PRC2-associated chromatin marks,
suggesting that Lsh and DNA methylation are important for complete assembly and activity of the …

DNA methylation properties: consequences for pharmacology

M Szyf - Trends in pharmacological sciences, 1994 - cell.com
… One candidate that may play an important role is DNA methylationmethylation patterns
suggests that DNA methylation patterns are inherited during replication. This is because the DNA

Genome-wide analysis of DNA methylation patterns

D Zilberman, S Henikoff - 2007 - journals.biologists.com
DNA methylation has an important role in many aspects of biology,including development …
of DNA methylation patterns. A study published in early 2006 estimated that DNA methylation

Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation

DJ Weisenberger, M Velicescu, JC Cheng… - Molecular Cancer …, 2004 - AACR
DNA (4–6), suggesting that it has maintenance activity and is responsible for copying the
DNA methylation pattern on newly synthesized DNA. … highlight a potentially important role of …

Methods in DNA methylation profiling

T Zuo, B Tycko, TM Liu, HJL Lin, THM Huang - Epigenomics, 2009 - Taylor & Francis
… Metastable and somatically heritable patterns of DNA methylation provide an important
important discoveries will continue to be made using genome-wide DNA methylation profiling. …

DNA methylation and systemic lupus erythematosus

E Balada, J ORDI‐ROS… - Annals of the New …, 2007 - Wiley Online Library
… the importance of DNA hypomethylation in the etiology of systemic lupus erythematosus (SLE).
Different enzymes linked to the DNA methylation … to modify their methylation patterns. …

DNA methylation detection: bisulfite genomic sequencing analysis

Y Li, TO Tollefsbol - Epigenetics protocols, 2011 - Springer
DNA methylation, which most commonly occurs at the C5 … DNA methylation is often
associated with loss of DNA … The importance of DNA methylation creates an urgent demand for …

The roles of DNA methylation in the stages of cancer

KW McMahon, E Karunasena, N Ahuja - The Cancer Journal, 2017 - journals.lww.com
… Therefore, DNA methylation can play an important role in many aspects of carcinogenesis,
but it also regulates many facets of the later stages of cancer pathophysiology, as we …