Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers

F Islam, Z Dehbia, M Zehravi, R Das… - Chemico-Biological …, 2023 - Elsevier
therapeutic effect of indole alkaloids is attributed to their basic properties, which result from a
pyrrole ring containing nitrogen atoms [20,21]. Indole alkaloids … of these indole alkaloids, for …

Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets

R Qin, FM You, Q Zhao, X Xie, C Peng, G Zhan… - Journal of hematology & …, 2022 - Springer
indole alkaloids and the combined strategies of multiple agents (eg, 3,10-dibromofascaplysin
combined with olaparib) to exhibit therapeutic … death by indole alkaloids against different …

[HTML][HTML] Indole alkaloids from plants as potential leads for antidepressant drugs: A mini review

HA Hamid, ANM Ramli, MM Yusoff - Frontiers in pharmacology, 2017 - frontiersin.org
… Studies on the effectiveness of indole alkaloids in treating … to the benefits of the therapeutic
usefulness of plants endowed … of indole alkaloids which are valuable starting points for the …

The therapeutic prospects of naturally occurring and synthetic indole alkaloids for depression and anxiety disorders

S Munir, A Shahid, B Aslam, UA Ashfaq… - Evidence‐Based …, 2020 - Wiley Online Library
… Moreover, the chemical synthesis of indole alkaloids is also proposed as indole alkaloids
a valuable starting point to develop effective alternatives for the therapeutic management of …

Analysis of alkaloids (indole alkaloids, isoquinoline alkaloids, tropane alkaloids)

P Dey, A Kundu, A Kumar, M Gupta, BM Lee… - Recent advances in …, 2020 - Elsevier
… This therapeutic potential of alkaloids grows up their industrial … Other indole alkaloids also
possess essential and potent … Marine-derived indole alkaloids are very promising and an …

[HTML][HTML] Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy

ML Luo, W Huang, HP Zhu, C Peng, Q Zhao… - Biomedicine & …, 2022 - Elsevier
… Then, we focus on mechanisms by which indole alkaloids can … protective role at early time
points, resulting in autophagic cell … agents for cancer therapy. In summary, we hope that more …

Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view

N Chadha, O Silakari - European Journal of Medicinal Chemistry, 2017 - Elsevier
indole alkaloids, indole based FDA approved drugs and clinical trial candidates having diverse
therapeutic … has a melting point range of 52–54 C (126–129 F) and boiling point of 254 C. …

Indole alkaloids from marine sources as potential leads against infectious diseases

PHB Franca, DP Barbosa, DL da Silva… - BioMed research …, 2014 - Wiley Online Library
… Therefore this review highlighted some marine indole alkaloids which may be considered
as potential starting points for the development of novel agents for the treatment of infectious …

Marine-derived indole alkaloids and their biological and pharmacological activities

JT Wibowo, P Ahmadi, SI Rahmawati, A Bayu… - Marine Drugs, 2021 - mdpi.com
… This review reports the indole alkaloids isolated during the … indole alkaloids reported from
2016 to 2021 were collected from various scientific databases. A total of 186 indole alkaloids

Indole alkaloids and semisynthetic indole derivatives as multifunctional scaffolds aiming the inhibition of enzymes related to neurodegenerative diseases–a focus on …

L Carlos Klein-Junior… - Current Topics in …, 2014 - ingentaconnect.com
… Abstract: Indole alkaloids and synthetic indole derivatives are well known for their therapeutic
… be a chemotaxonomic marker for the genus and points to a close relationship between the …