… 50 years as an anticancer therapeutic and a true lead for … The antihypertensive indole
alkaloid reserpine from the genus … for human use and at some point of time this popularity was …

… Indole is an essential branch of alkaloids widely presented in many natural resources and
other alkaloid … It has been reported that indole alkaloids can control cell death by regulating …

… such as taxanes and the vinca alkaloids were seminal landmarks in natural product drug
discovery. Jerantinine A (JA), a novel Aspidosperma alkaloid isolated from plant species …

… studies point to the fact that large or small structural differences among analogous indole
alkaloids, … In the present study, the antiplasmodial activity of structurally related indole alkaloids …

… therapy – the dimeric terpenoid indole alkaloids vinblastine and vincristine. The study of C.
roseus further revealed two other terpenoid indole alkaloids … At this point, anhydrovinblastine …

… One point mutation (Asn722Ser) was identical to the mutation found in human DNA … while
the two other point mutations (Asn421Lys, Leu530Ile) also conferred camptothecin resistance. …

… Herein, pyrazino[2,1-b]quinazoline-3,6-diones containing indole alkaloids were explored
for their antiparasitic potential against Plasmodium falciparum, Trypanosoma brucei, and …

… Our single point mutation (D31H) is located at the beginning of the pTMD1 domain (ER …
DENV and yellow fever virus (23), proposing it as a potential vulnerable point for these members. …

… indole alkaloids among different plant species is presented in order of increasing molecular
weight in Table 1. The alkaloid structures with their melting points and [… on melting points and …

… In this study, we evaluated the effect of the indole-alkaloid aristoteline (ARI), isolated from
leaves of Maqui, on vascular reactivity of isolated aortic rings from normotensive rats. ARI …