Quantification of repertoire diversity of influenza-specific epitopes with predominant public or private TCR usage

K Kedzierska, EB Day, J Pi, SB Heard… - The Journal of …, 2006 - journals.aai.org
… choriomeningitis virus (LCMV) or mouse hepatitis virus (MHV), the influenza-specific TCR
repertoire included … directed against an immunodominant influenza virus CTL epitope. …

Narrowing of human influenza A virus-specific T cell receptor α and β repertoires with increasing age

A Gil, MB Yassai, YN Naumov, LK Selin - Journal of virology, 2015 - Am Soc Microbiol
… in the influenza virus M1-specific TCR repertoire in older … of both the VA and VB TCR
repertoires simultaneously in the same … not only that the TCR repertoires were narrowed in older …

[HTML][HTML] Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection

S Sant, L Grzelak, Z Wang, A Pizzolla… - Frontiers in …, 2018 - frontiersin.org
TCRs directed against the most prominent human influenza … We dissected memory TCR
repertoires directed toward A2 + … + T cell repertoires to A2 + M1 58 CD8 + TCRs during acute …

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus

EJ Yager, M Ahmed, K Lanzer, TD Randall… - The Journal of …, 2008 - rupress.org
… and young mice 10 d after influenza virus infection to determine CDR3 length diversity. We
used 22 Vβ primers to span virtually the entire TCR β-chain repertoire, with the exception of …

[HTML][HTML] Profiling the TRB and IGH repertoire of patients with H5N6 Avian Influenza Virus Infection by high-throughput sequencing

W Peng, S Liu, J Meng, J Huang, J Huang, D Tang… - Scientific Reports, 2019 - nature.com
TCR and BCR repertoire after infectious states. Conversely, H5N6 avian influenza viruses-specific
TCR… we used HTS of the human TCR/BCR heavy chain repertoire to gain insight into T…

In VivoLongitudinal Analysis of a Dominant TCR Repertoire Selected in Human Response to Influenza Virus

A Prevost-Blondel, R Lengagne, F Letourneur… - Virology, 1997 - Elsevier
… of TCR Vb17 and a high degree of diversity in Jb usage within the influenza virus matrix …
In contrast, in the course of a study on the cellular response to influenza A virus, we found …

[HTML][HTML] Impact of ageing on the response and repertoire of influenza virus-specific CD4 T cells

KG Lanzer, LL Johnson, DL Woodland, MA Blackman - Immunity & Ageing, 2014 - Springer
influenza virus infection of aged mice was associated with perturbations in the T cell receptor
repertoire, … We first characterized the NP-specific CD4 T cell receptorrepertoire in detail …

Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes

SC Clute, YN Naumov, LB Watkin, N Aslan… - The Journal of …, 2010 - journals.aai.org
… with a narrow oligoclonal TCR repertoire (6). … influenza virus bearing a point mutation in a
cross-reactive epitope and with lymphocytic choriomeningitis virus (LCMV) and Pichinde virus (…

Human γδ Tcell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation

S Sant, MR Jenkins, P Dash, KA Watson… - Clinical & …, 2019 - Wiley Online Library
influenza A viruses. Although (as compared to TCRαβ sets) γδ T cells display more limited
TCR repertoires… ), in adults (diverse γδ TCRs within the predominant γ9δ2 segment but limited …

Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire

K Daly, P Nguyen, DL Woodland… - Journal of virology, 1995 - Am Soc Microbiol
… that the limited TCR repertoire in the TG8.1 mice profoundly affected the immunodominance
of class I epitopes following inffuenza virus infection. Analysis of inffuenza virus-specific T-…