Quadrupling the dose of inhaled corticosteroid to prevent asthma exacerbations: a randomized, double-blind, placebo-controlled, parallel-group clinical trial

J Oborne, K Mortimer, RB Hubbard… - American journal of …, 2009 - atsjournals.org
… or no change in dose of inhaled corticosteroid in the active and placebo groups, respectively.
… after using the study inhaler to arrange collection of the used inhaler and completed diary …

Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study

M Baraket, BGG Oliver, JK Burgess, S Lim, GG King… - Respiratory …, 2012 - Springer
… 22 mild or moderate asthmatic adult subjects (corticosteroid free for > 2 months) participated
in a randomized, parallel group study to compare effects of fluticasone propionate (FP) 200 …

… salmeterol as add-on therapy to inhaled corticosteroids for patients with moderate symptomatic asthma: two replicate, double-blind, placebo-controlled, parallel-group …

HAM Kerstjens, TB Casale, ER Bleecker… - The Lancet …, 2015 - thelancet.com
… plus LABA fixed-dose combinations were switched to the inhaled corticosteroid mono-product …
inhalation of inhaled corticosteroids if regular pre-study dosing of inhaled corticosteroids

… inhaler triple therapy versus inhaled corticosteroid plus long-acting β2-agonist therapy for chronic obstructive pulmonary disease (TRILOGY): a double-blind, parallel …

D Singh, A Papi, M Corradi, I Pavlišová, I Montagna… - The Lancet, 2016 - thelancet.com
… evidence for the clinical benefits of stepping up patients with COPD from an inhaled
corticosteroid/long-acting β 2 -agonist combination treatment to triple therapy using a single inhaler. …

… -group study of budesonide inhalation suspension in adolescents and adults with moderate to severe persistent asthma previously receiving inhaled corticosteroids …

K Murphy, M Noonan, PE Silkoff, T Uryniak - Clinical therapeutics, 2007 - Elsevier
… receiving inhaled corticosteroids (ICSs) by dry powder inhaler (DPI) or metered-dose inhaler
(… among groups using an ANCOVA model. P ≤ 0.05 was considered statistically significant. …

… an inhaled corticosteroid, budesonide, and a β2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomized, double-blind, parallel-group …

LA Laitinen, A Laitinen, T Haahtela - Journal of allergy and clinical …, 1992 - Elsevier
… of an inhaled corticosteroid, budesonide, and an inhaled [32-… randomized, double-blind,
parallel-group trial. Seven patients … index observed after inhaled corticosteroid treatment in the …

A randomized, double-blind, double-dummy, parallel-group, multicenter, dose-reduction trial of the minimal effective doses of budesonide and fluticasone dry-powder …

P Kuna - Clinical therapeutics, 2003 - Elsevier
… Background: Inhaled corticosteroids are established first-line anti-inflammatory treatment
for asthma. Clinical trials comparing inhaled corticosteroids must take into consideration that …

The effect of umeclidinium added to inhaled corticosteroid/long-acting β2-agonist in patients with symptomatic COPD: a randomised, double-blind, parallel-group …

AR Sousa, JH Riley, A Church, CQ Zhu… - NPJ Primary Care …, 2016 - nature.com
Benefits of triple therapy with a long-acting muscarinic antagonist (LAMA), added to inhaled
corticosteroid (ICS)/long-acting β 2-agonist (LABA), have been demonstrated. Limited data …

Stepping down inhaled corticosteroids in asthma: randomised controlled trial

G Hawkins, AD McMahon, S Twaddle, SF Wood, I Ford… - BMj, 2003 - bmj.com
… , double blind, parallel group trial over a period of one year. … Table 4 shows data on use of
inhaled corticosteroids for 243 … annual dose of inhaled corticosteroid between the two groups (…

A phase IIb, randomised, parallel-group study: the efficacy, safety and tolerability of once-daily umeclidinium in patients with asthma receiving inhaled corticosteroids

E Kerwin, S Pascoe, Z Bailes, R Nathan… - Respiratory …, 2020 - Springer
… treatment with systemic corticosteroids, urgent care visits or hospitalisations [2]. The Global
Initiative for Asthma (GINA) 2019 strategy report recommends inhaled corticosteroids (ICS) …