… However, a systematic review found no reduction in bone mineral density or increase in
fractures in COPD patients treated for up to 3 years with ICS [75]. An epidemiological study …

… Reports dealing with the systemic effects of inhaled corticosteroids on adrenal gland, …
reviewed where appropriate. Studies were included that contained evaluable data on systemic …

Context Recent studies of inhaled corticosteroid (ICS) therapy for managing stable chronic
obstructive pulmonary disease (COPD) have yielded conflicting results regarding survival …

… The findings of this systematic review suggest that inhaled corticosteroids improve patient
outcomes in COPD. Regular use of inhaled corticosteroids in the doses employed in these …

… inhaled corticosteroid treatment in patients with COPD with respect to health outcomes.
Contrary to previous systematic reviews, because our review … of inhaled corticosteroid treatment …

… rapid systematic review to evaluate whether pre-morbid use or continued administration of
inhaled steroids … The review was conducted using the PRISMA (Preferred Reporting Items for …

… Despite previous reviews reporting that in acute settings the risk of hospital admission is
reduced with the use of high doses of inhaled corticosteroids (ICS), this evidence has not …

… Comparative clinical trials of inhaled corticosteroids and systematic reviews for efficacy
comparisons were evaluated. Extensive literature reviews, meta-analyses, and selected clinical …

… Funding: This manuscript presents a systematic review commissioned by Asthma UK (AUK-PG-2012-181),
www.asthma.org.uk, and the authors are grateful to the Asthma UK Research …

… corticosteroids; however, the use of ICSs is not free from possible complications. In this
systematic review … ; and an increased risk of some systemic effects such as respiratory infections (…