[HTML][HTML] Skeletal muscle “mitochondrial deficiency” does not mediate insulin resistance
JO Holloszy - The American journal of clinical nutrition, 2009 - Elsevier
… of insulin-resistant individuals than in normal individuals (6, 13). In keeping with the concept
that mitochondrial deficiency causes insulin resistance… in muscle insulin resistance results in …
that mitochondrial deficiency causes insulin resistance… in muscle insulin resistance results in …
Mitochondrial deficiency is associated with insulin resistance
BH Goodpaster - Diabetes, 2013 - Am Diabetes Assoc
… In summary, mitochondrial “deficiency” is not merely a … The most common forms of human
skeletal muscle insulin resistance … Impairments in mitochondrial energetics have been linked to …
skeletal muscle insulin resistance … Impairments in mitochondrial energetics have been linked to …
Altered mitochondrial function in insulin-deficient and insulin-resistant states
GN Ruegsegger, AL Creo, TM Cortes… - The Journal of …, 2018 - Am Soc Clin Investig
… Our primary aim is to broadly highlight how insulin deficiency in T1D and insulin resistance
… mitochondrial function, primarily in skeletal muscle. We also provide data on mitochondrial …
… mitochondrial function, primarily in skeletal muscle. We also provide data on mitochondrial …
“Deficiency” of mitochondria in muscle does not cause insulin resistance
JO Holloszy - Diabetes, 2013 - Am Diabetes Assoc
… the onset of the insulin resistance. It … mitochondrial deficiency precedes insulin resistance
in humans, because T2DM patients and obese insulin resistant individuals are insulin resistant …
in humans, because T2DM patients and obese insulin resistant individuals are insulin resistant …
Role of mitochondrial dysfunction in insulin resistance
J Kim, Y Wei, JR Sowers - Circulation research, 2008 - Am Heart Assoc
… insulin resistance in classic and nonclassic insulin target tissues. Insulin resistance emanating
from mitochondrial … In fact, eNOS-deficient mice are insulin resistant and hypertensive and …
from mitochondrial … In fact, eNOS-deficient mice are insulin resistant and hypertensive and …
Mitochondrial dysfunction, insulin resistance, and type 2 diabetes mellitus
MA Abdul-Ghani, RA DeFronzo - Current diabetes reports, 2008 - Springer
… in mitochondrial … mitochondrial defect in insulin-resistant individuals. Electron microscopic
studies have demonstrated morphological abnormalities in mitochondria in insulinresistant …
studies have demonstrated morphological abnormalities in mitochondria in insulinresistant …
Insulin resistance and mitochondrial dysfunction
A Gonzalez-Franquesa, ME Patti - Mitochondrial Dynamics in …, 2017 - Springer
… linking mitochondrial dysfunction and insulin resistance, and review the potential for mitochondrial
targets as a … Thus, incretin deficiency is a likely contributor to progressive decreases in …
targets as a … Thus, incretin deficiency is a likely contributor to progressive decreases in …
Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance
D Zhang, ZX Liu, CS Choi, L Tian… - Proceedings of the …, 2007 - National Acad Sciences
… However, it is unclear whether the reduced mitochondrial function is a primary or acquired …
in mitochondrial β-oxidation can cause insulin resistance, we studied mice with a deficiency of …
in mitochondrial β-oxidation can cause insulin resistance, we studied mice with a deficiency of …
Is mitochondrial dysfunction a cause of insulin resistance?
N Turner, LK Heilbronn - Trends in Endocrinology & Metabolism, 2008 - cell.com
… to the theory that compromised mitochondrial oxidative function, … insulin resistance. Here,
we review the latest findings regarding the link between mitochondrial metabolism and insulin …
we review the latest findings regarding the link between mitochondrial metabolism and insulin …
Docosahexaenoic acid affects insulin deficiency-and insulin resistance-induced alterations in cardiac mitochondria
S Ovide-Bordeaux, A Grynberg - American Journal of …, 2004 - journals.physiology.org
… mitochondrial function was more pronounced in the insulin-deficient state than in insulin
resistance… The modification of fatty acid composition of cardiac and mitochondrial membranes …
resistance… The modification of fatty acid composition of cardiac and mitochondrial membranes …
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