Integrated microbiota and metabolite profiles link Crohn's disease to sulfur metabolism

A Metwaly, A Dunkel, N Waldschmitt, ACD Raj… - Nature …, 2020 - nature.com
… We identified metabolic mechanisms that underline microbiota changes in CD patients who
… on integrated microbiota-metabolite networks, the identification of unknown metabolites

Integration of Gut Microbiota and Metabolomics for Chinese Medicine Research: Opportunities and Challenges

W Feng, J Liu, H Cheng, C Peng - Chinese Journal of Integrative Medicine, 2022 - Springer
… Focusing on gut microbiota and metabolites, we depict the … change of gut microbiota and
metabolites in body might happen in different timescale, and the content change of metabolites

Integrated metagenomics and metabolomics analysis illustrates the systemic impact of the gut microbiota on host metabolism after bariatric surgery

Y Han, G Kim, E Ahn, S Jung, Y Jung… - Diabetes, Obesity …, 2022 - Wiley Online Library
… Additionally, in linear mixed model analysis to find time-specific microbiota changes, when
… to verify the correlation between serum metabolites and gut microbiota in our findings. …

Metabolic model-based integration of microbiome taxonomic and metabolomic profiles elucidates mechanistic links between ecological and metabolic variation

C Noecker, A Eng, S Srinivasan, CM Theriot… - …, 2016 - Am Soc Microbiol
… analysis of the vaginal microbiota, including successful prediction of metabolite variation and
the … , are suggestive of environmentally regulated metabolite changes that cause taxonomic …

The intestinal metabolome: an intersection between microbiota and host

LK Ursell, HJ Haiser, W Van Treuren, N Garg… - Gastroenterology, 2014 - Elsevier
microbiota determines levels of specific metabolites, how the … , the computational challenges
in integrating data from multiple … cases in which changes in the gut microbiota alter host …

Integrative analysis of metabolome and gut microbiota in diet-induced hyperlipidemic rats treated with berberine compounds

M Li, X Shu, H Xu, C Zhang, L Yang, L Zhang… - Journal of Translational …, 2016 - Springer
Changes in these metabolites suggested the enhancement in fatty acid and cholesterol …
According to the alterations in metabolites from different types of sample and gut microbiota

Microbiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

L Ning, YL Zhou, H Sun, Y Zhang, C Shen… - Nature …, 2023 - nature.com
… the relationship between gut microbiota and metabolites, we construct … microbiota and host
co-metabolism 38 ,we further sought to explore the spectrum of changes in fecal metabolites

[HTML][HTML] Integrated microbiome and metabolome analysis reveals a novel interplay between commensal bacteria and metabolites in colorectal cancer

Y Yang, BB Misra, L Liang, D Bi, W Weng, W Wu… - Theranostics, 2019 - ncbi.nlm.nih.gov
… Since the CRC patients demonstrated signature microbiota associated with disease, we …
Analysis of the differentially accumulated and significantly changed metabolites in the H …

Integrated metagenomic and metabolomic analysis reveals distinct gut-microbiome-derived phenotypes in early-onset colorectal cancer

C Kong, L Liang, G Liu, L Du, Y Yang, J Liu, D Shi, X Li… - Gut, 2023 - gut.bmj.com
… our hypothesis that altered gut microbiota and metabolites in young individuals may interact
… KO genes and metabolites were associated with changes in microbiota in CRC faeces, and …

Integrated analysis of gut microbiota and metabolomic profiling in colorectal cancer metastasis

Y Xia, L Duan, X Zhang, Y Niu… - Environmental …, 2024 - Wiley Online Library
metabolites. The criteria set for identifying significant metabolites included a minimum fold
change … bacteria and metabolites, integrating gut sequencing data with metabonomic insights. …