Single-cell transcriptome analysis reveals inter-tumor heterogeneity in bilateral papillary thyroid carcinoma

T Wang, J Shi, L Li, X Zhou, H Zhang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
… In conclusion, our study revealed great inter-tumor heterogeneity in the cellular composition
and molecular phenotype of the TME in bilateral PTC. Prognostic enriched pathway …

Dynamic cancer cell heterogeneity: diagnostic and therapeutic implications

V Jacquemin, M Antoine, G Dom, V Detours… - Cancers, 2022 - mdpi.com
… in different patients (inter-tumor). … , papillary and follicular thyroid carcinomas have low
overall mortality but are likely to relapse. Thyroid carcinomas present good models for other tumors

The immune landscape of papillary thyroid cancer in the context of autoimmune thyroiditis

F Pani, P Caria, Y Yasuda, M Makoto, S Mariotti… - Cancers, 2022 - mdpi.com
… The association between papillary thyroid cancer and … Papillary thyroid carcinoma is an
excellent model for studying … the heterogeneity and molecular evolution of thyroid cancer. …

An individualized protein-based prognostic model to stratify pediatric patients with papillary thyroid carcinoma

Z Wang, H Wang, Y Zhou, L Li, M Lyu, C Wu… - Nature …, 2024 - nature.com
… Pediatric papillary thyroid carcinomas (PPTCs) exhibit high inter-tumor heterogeneity and
… Patients with bilateral PTC underwent total thyroidectomy and bilateral central lymph node …

Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells

A Tourneur, J Rodrigues Vitoria, M Saiselet, L Craciun… - bioRxiv, 2024 - biorxiv.org
… While single cell transcriptomics may resolve this heterogeneity, it is potentially confounded
by batch effects whose correction may dampen inter-tumor variations. We profiled ATCs and …

TIPARP as a prognostic biomarker and potential immunotherapeutic target in male papillary thyroid carcinoma

J Zhang, X Zhou, F Yao, JL Zhang, Q Li - Cancer Cell International, 2024 - Springer
… We obtained raw single-cell RNA-seq data for 7 male papillary thyroid carcinoma samples
with lymph node metastasis from GEO datasets GSE193581, GSE163203, and GSE191288. …

[图书][B] The Impact of Inter-and Intra-Tumoral Heterogeneity on Thetreatment of Cancer

P Gopal - 2019 - search.proquest.com
… intratumoral heterogeneity. Taken together, these studies begin to elucidate the inter-tumor
of some cancers and the impact of this heterogeneity on therapeutic resistance in cancer. …

A computational approach to assessing the prognostic implications of BRAF and RAS mutations in patients with papillary thyroid carcinoma

T Haghzad, B Khorsand, S Adeleh Razavi, M Hedayati - Endocrine, 2024 - Springer
Papillary thyroid carcinoma (PTC) is the most common thyroid cancer, posing a growing
clinical challenge. PTC exhibits two age-related peaks, with established risk factors including …

Exploring the advances of single-cell RNA sequencing in thyroid cancer: a narrative review

JK Tan, WA Awuah, S Roy, T Ferreira, A Ahluwalia… - Medical Oncology, 2023 - Springer
… of extensive vascular-immune crosstalk within the multicellular tumour ecosystem, thereby
enhancing our understanding of cellular heterogeneity and the TME of thyroid cancer [20]. …

Analysis of therapeutic response of iodine positive metastasis lymph nodes in differentiated thyroid cancer after 131I treatment

MEI Xiaoran, F Fang, W Hui, WEI Zhixiao - China Oncology, 2022 - china-oncology.com
… Single-cell transcriptome analysis reveals inter-tumor heterogeneity in bilateral papillary
thyroid carcinoma[J]. Front Immunol, 2022, 13: 840811. [20] 卢承慧, 李 娇, 刘新峰, 等. …