… We have highlighted the context-dependent effects of reactive oxygen species throughout
the life of a neuron, summarizing the latest advancements in the field as well as ongoing …

… into neurons in high concentrations of oxygen in vitro [68], and that oxygen pressure and …
of neurons [69, 70]. Additionally, PC12 cells grown in 50% O 2 (hyperoxia) show levels of …

… highlights the point that both oxidative stress and lifespan or health span may be connected,
… Indeed, ROS fulfill several criteria of second messenger molecules, such as a short life-time …

… to immediate neuronal death, while chronic insults induce a much slower process resulting
in neuronal death from cumulative adverse exposure to reactive oxygen species (ROS) or …

… of the ATP required for normal neuronal function. In accordance with this … and/or generation
of reactive oxygen species plays a major … dysfunction in a number of neuronal disease states. …

… in reactive oxygen species (ROS) that peaked at 3 hr after sympathetic neurons were deprived
of … During injections, the medium on the neurons was Leibovitz's L-15 (Life Technologies), …

… dopaminergic neurons in the substantia nigra pars compacta (SNpc), which leads to a …
maintain the patient’s autonomy and quality of life. Several of the approved drugs for PD are quite …

… in the etiology of aging, cancer and degenerative neuronal diseases is also described. …
oxygen (k = 6 x 106M-2s-1), its lifetime increases significantly under physiologically low oxygen …

… We have investigated the role of reactive oxygen species (… isolated rat cerebellar granule
cell neurons, studied by flow … viability in acutely dissociated neurons subjected to ischemia …

… delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death.
… Mitochondria: releasing power of life and unleashing the machineries of death. Cell 112: …