Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents

DP Tashkin, LM Fabbri - Respiratory research, 2010 - Springer
… For patients with moderate-to-severe COPD, long-acting … Inhaled long-acting β 2 -agonists
(LABAs) have been … the role and future of long-acting β 2 -agonists (LABAs) in the …

The FDA and safe use of long-acting beta-agonists in the treatment of asthma

BA Chowdhury, G Dal Pan - New England Journal of Medicine, 2010 - Mass Medical Soc
… For over a decade, the Food and Drug Administration (FDA) and the medical community have
discussed how to safely use long-acting beta-agonists (LABAs) — drugs designed to provide …

Regular treatment with long acting beta agonists versus daily regular treatment with short acting beta agonists in adults and children with stable asthma

EH Walters, JAE Walters, PG Gibson… - Cochrane Database …, 1996 - cochranelibrary.com
… inhaled long acting beta agonists with regular use of inhaled short acting beta agonists in …
from the regular use of inhaled long acting beta agonists compared with inhaled short acting

Why are long-acting beta-adrenoceptor agonists long-acting?

GP Anderson, A Linden, KF Rabe - European Respiratory …, 1994 - Eur Respiratory Soc
… Plasmalemma diffusion microkinetic theory of the duration of action of beta2-adrenoceptor
agonists To understand the duration of action of beta2-adrenoceptor agonists, we propose …

Meta-analysis: effect of long-acting β-agonists on severe asthma exacerbations and asthma-related deaths

SR Salpeter, NS Buckley, TM Ormiston… - Annals of internal …, 2006 - acpjournals.org
… Effects of the long acting beta agonist formoterol on asthma control in asthmatic patients
using inhaled corticosteroids. The Netherlands and Canadian Formoterol Study Investigators. …

Pharmacology of long-acting beta-agonists.

M Johnson - Annals of Allergy, Asthma & Immunology: Official …, 1995 - europepmc.org
… of action. The pharmacologic profiles of these drugs result from prolonged activation of beta
2-adrenoceptors, leading to long-… The long-acting beta 2-agonists represent a therapeutic …

Safety of long-acting beta-agonists—an urgent need to clear the air

FD Martinez - New England Journal of Medicine, 2005 - Mass Medical Soc
… How do we reconcile in clinical practice the established beneficial effects of long-acting
beta-agonists on asthma control with their rare potential for contributing to severe illness or …

Combination long-acting β-agonists and inhaled corticosteroids compared with long-acting β-agonists alone in older adults with chronic obstructive pulmonary …

AS Gershon, MA Campitelli, R Croxford, MB Stanbrook… - Jama, 2014 - jamanetwork.com
… To estimate the long-term benefits of combination long-acting β-agonists (LABAs) and … )
and those who were not receiving inhaled long-acting anticholinergic medication (difference in …

Risks of long-acting beta-agonists in achieving asthma control

JM Drazen, PM O'Byrne - New England Journal of Medicine, 2009 - Mass Medical Soc
long-acting beta-agonists (LABAs). The meeting is described in detail in a Perspective in
this issue of the Journal by Kramer, 1 who points out that decision making by the advisers and …

Long-acting beta-agonists with and without inhaled corticosteroids and catastrophic asthma events

SR Salpeter, AJ Wall, NS Buckley - The American journal of medicine, 2010 - Elsevier
… It is unclear whether long-acting β-agonists with concomitant inhaled corticosteroids
increase asthma-related intubations and deaths. We pooled data on long-acting β-agonists with …