Material design for lymph node drug delivery
… Although they are less prevalent than in the paracortex because they are replaced by
follicular dendritic cells during lymph node development, conduits are an important pathway for …
follicular dendritic cells during lymph node development, conduits are an important pathway for …
Multi-compartment 3D-cultured organ-on-a-chip: towards a biomimetic lymph node for drug development
… However, in spite of the large number of models proposed for drug development … of the
lymph node (LN) has not been provided yet [13,19]. Only recently has the need for developing an …
lymph node (LN) has not been provided yet [13,19]. Only recently has the need for developing an …
Overcoming transport barriers for interstitial-, lymphatic-, and lymph node-targeted drug delivery
… characteristics developed to … lymphatic vessels and the lymph nodes to which they drain.
This review describes the current state of interstitial-, lymphatic-, and lymph node-targeted drug …
This review describes the current state of interstitial-, lymphatic-, and lymph node-targeted drug …
Nanomaterial-based drug delivery system targeting lymph nodes
Z Cheng, H Que, L Chen, Q Sun, X Wei - Pharmaceutics, 2022 - mdpi.com
… A well-designed lymphatic-targeted system … , development of nanotechnologies and
emerging biomaterials have gained increasing attention in developing lymph-node-targeted drug-…
emerging biomaterials have gained increasing attention in developing lymph-node-targeted drug-…
Programmable multistage drug delivery to lymph nodes
… , LNs present some of the same types of problem for drug delivery as the brain. Possessed of
no … We show here the development of a two-stage approach inspired by the way particulate …
no … We show here the development of a two-stage approach inspired by the way particulate …
Pharming the human lymph node
MC Glassy, ME McKnight - … Opinion on Investigational Drugs, 1994 - Taylor & Francis
… development. Based on the hypothesis that lymphocytes isolated from regional draining
lymph nodes … Therefore, AgSKl can be considered a candidate for drug development and our …
lymph nodes … Therefore, AgSKl can be considered a candidate for drug development and our …
Lymph nodes-on-chip: promising immune platforms for pharmacological and toxicological applications
… Despite the fact that most of the developed in vitro lymph node models have not been … do
hold a huge potential to revolutionize drug discovery and drug development. In particular, the …
hold a huge potential to revolutionize drug discovery and drug development. In particular, the …
Engineering strategies for lymph node targeted immune activation
Y Chen, S De Koker, BG De Geest - Accounts of chemical …, 2020 - ACS Publications
… increase nanoparticle delivery to lymph nodes: (1) direct lymph node injection, (… lymph
nodes, and multiple studies have demonstrated its capability in enhancing immunostimulant drugs…
nodes, and multiple studies have demonstrated its capability in enhancing immunostimulant drugs…
Vaccine delivery systems toward lymph nodes
Y Ding, Z Li, A Jaklenec, Q Hu - Advanced drug delivery reviews, 2021 - Elsevier
… as carriers are widely developed to achieve efficient lymph node targeting and improve
vaccine-… of lymph node targeting vaccine delivery based on the anatomy of lymph nodes and …
vaccine-… of lymph node targeting vaccine delivery based on the anatomy of lymph nodes and …
Innovations in lymph node targeting nanocarriers
… that have been developed to enable lymph node delivery are discussed. … lymphatic drug
delivery systems [21], we describe in this review the lymphatic physiology relevant to lymph node…
delivery systems [21], we describe in this review the lymphatic physiology relevant to lymph node…
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