mRNA vaccine for cancer immunotherapy

L Miao, Y Zhang, L Huang - Molecular cancer, 2021 - Springer
… therapeutic outcomes of mRNA cancer vaccines achieved in … advancing of mRNA vaccines
for cancer immunotherapy in … and existing challenges of mRNA cancer vaccines and future …

mRNA vaccines for cancer immunotherapy

YL Vishweshwaraiah, NV Dokholyan - Frontiers in immunology, 2022 - frontiersin.org
… for mRNA cancer vaccine development. We highlight the platforms available for delivery of
the mRNA vaccines … Finally, we discuss the limitations of mRNA cancer vaccines and future …

Potentialities and challenges of mRNA vaccine in cancer immunotherapy

LJ Duan, Q Wang, C Zhang, DX Yang… - Frontiers in …, 2022 - frontiersin.org
… In the past decades, modifications on mRNA structure and … advancements of mRNA vaccines
in cancer immunotherapy and the … of mRNA vaccines for the successful treatment of cancer. …

mRNA vaccines: The dawn of a new era of cancer immunotherapy

Z Deng, Y Tian, J Song, G An, P Yang - Frontiers in Immunology, 2022 - frontiersin.org
mRNA cancer vaccines that are candidates for cancer treatment and discuss clinical trials in
the field of tumor immunotherapy. … of action by which mRNA vaccines destroy tumors as well …

mRNA therapeutics in cancer immunotherapy

JD Beck, D Reidenbach, N Salomon, U Sahin… - Molecular cancer, 2021 - Springer
mRNA vaccines encode the full or partial sequence of a TSA … The feasibility of mRNA-based
cancer vaccination was first … studies explored mRNA for anti-cancer vaccination, either by …

RNA‐based vaccines in cancer immunotherapy

MA McNamara, SK Nair, EK Holl - Journal of immunology …, 2015 - Wiley Online Library
… In this review, we will explain why RNA vaccines represent an attractive platform for cancer
… strategies for delivery of mRNA vaccines, with a focus on their role in cancer immunotherapy. …

Personalized anti-cancer vaccine combining mRNA and immunotherapy tested in melanoma trial

T Carvalho - Nat Med, 2023 - nature.com
… all forms of immunotherapy. BioNTech also has its own mRNA vaccine program for melanoma.
Interestingly, BioNTech has shifted to unmodified RNA nucleotides for its anti-cancer vac…

mRNA in cancer immunotherapy: beyond a source of antigen

L Van Hoecke, R Verbeke, H Dewitte, I Lentacker… - Molecular cancer, 2021 - Springer
… in vitro transcribed mRNA was on development of cancer vaccines, using … , mRNA vaccines
using LNP technologies for intramuscular administration are set to become the first vaccines

Clinical advances and ongoing trials of mRNA vaccines for cancer treatment

CL Lorentzen, JB Haanen, Ö Met, IM Svane - The Lancet Oncology, 2022 - thelancet.com
… Therapeutic cancer vaccines based on mRNA are well tolerated, and the inherent … vaccine
manufacture methods, renders mRNA vaccines a promising option for cancer immunotherapy. …

Messenger RNA vaccines for cancer immunotherapy: progress promotes promise

AL Huff, EM Jaffee, N Zaidi - The Journal of Clinical …, 2022 - Am Soc Clin Investig
… Thus far, mRNA vaccination strategies for cancer treatment have shown success in murine
cancer … A key consideration in developing mRNA vaccines for cancer treatment is the optimal …