Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine

DE Neafsey, M Juraska, T Bedford… - … England Journal of …, 2015 - Mass Medical Soc
… The RTS,S/AS01 vaccine targets the … has partial protective efficacy against clinical and
severe malaria disease in infants and children. We investigated whether the vaccine efficacy was …

Correlates of malaria vaccine efficacy

DI Stanisic, MBB McCall - Expert Review of Vaccines, 2021 - Taylor & Francis
efficacy against controlled human malaria infections (CHMI) and against naturally acquired
infections. Expert Opinion: Effective vaccination … disappointing efficacy of malaria vaccine

[HTML][HTML] Malaria prevention: from immunological concepts to effective vaccines and protective antibodies

IA Cockburn, RA Seder - Nature immunology, 2018 - nature.com
… that must be overcome to improve malaria-vaccine efficacy with current approaches. This …
review of all malaria-vaccine trials or to encompass the field of transmission-blocking vaccines (…

Reduced protective efficacy of a blood-stage malaria vaccine by concurrent nematode infection

Z Su, M Segura, MM Stevenson - Infection and immunity, 2006 - Am Soc Microbiol
efficacy of malaria vaccines in humans. We established a murine coinfection model involving
blood-stage Plasmodium chabaudi AS malaria … the protective efficacy of a malaria vaccine. …

The RTS, S malaria vaccine

S Casares, TD Brumeanu, TL Richie - Vaccine, 2010 - Elsevier
protection afforded by RTS,S and to build a more efficacious second generation vaccine
against malaria… This review will focus on current knowledge about the protective efficacy of RTS,…

Evaluation of SPf66 malaria vaccine efficacy in Brazil

M Urdaneta, A Prata, CJ Struchiner, CE Tosta, P Tauil… - 1998 - arca.fiocruz.br
… is to be a public health tool, we cannot base our conclusions on its efficacy against the
first episode, but on its overall efficacy. Overall protective efficacies of SPf66 malaria vaccine

Correlating efficacy and immunogenicity in malaria vaccine trials

MBB McCall, PG Kremsner, B Mordmüller - Seminars in Immunology, 2018 - Elsevier
protection in malaria vaccine development: Does immunogenicity predict malaria vaccine
efficacy … Have immunological correlates accelerated malaria vaccine development in the past …

[HTML][HTML] Pre-erythrocytic malaria vaccines: towards greater efficacy

AVS Hill - Nature Reviews Immunology, 2006 - nature.com
… current malaria vaccine reaches the levels of durable efficacy likely to be required for vaccine
… -liver-stage vaccines in combination produces much greater efficacy and this combination …

Genetic diversity and malaria vaccine design, testing and efficacy: preventing and overcoming 'vaccine resistant malaria'

SL Takala, CV Plowe - Parasite immunology, 2009 - Wiley Online Library
… and natural dynamics of vaccine antigen … malaria vaccines, allele-specific efficacy should
be measured as a key study endpoint, and this information used to inform subsequent vaccine

[HTML][HTML] Malaria vaccines: progress to date

DI Stanisic, MF Good - BioDrugs, 2023 - Springer
malaria vaccine and was shown to have modest efficacymalaria vaccine that is able to
induce long-lasting protective … factors including the complexity of the malaria parasite’s life-cycle, …