Research progress of long non-coding RNA GAS5 in malignant tumors

G Lin, T Wu, X Gao, Z He, W Nong - Frontiers in Oncology, 2022 - frontiersin.org
malignancy, poor prognosis, and drug resistance. Recent studies have demonstrated that
GAS5 can … In addition, GAS5 participates in regulating proliferation, invasion, and apoptosis …

The Non-Coding RNA GAS5 and Its Role in Tumor Therapy-Induced Resistance

GI Lambrou, K Hatziagapiou, A Zaravinos - International journal of …, 2020 - mdpi.com
… the down-regulation of GAS5 led to the rescue of primary and malignant T-lymphocytes from
GAS5 inhibits cell proliferation also through the miR-544/RUNX3 pathway [102], where it …

Long non‑coding RNA GAS5 in human cancer

X Yang, Z Xie, X Lei, R Gan - Oncology letters, 2020 - spandidos-publications.com
GAS5 is downregulated in a number of human malignancies. GAS5 can induce apoptosis
and inhibit the proliferative and metastatic properties of tumors. The exact molecular …

Long noncoding RNA GAS5 inhibits malignant proliferation and chemotherapy resistance to doxorubicin in bladder transitional cell carcinoma

H Zhang, Y Guo, Y Song, C Shang - Cancer chemotherapy and …, 2017 - Springer
… In summary, lncRNA GAS5 was a prognostic biomarker of disease free survival in BTCC …
inhibit malignant proliferation and resistance to doxorubicin in BTCC cells. LncRNA GAS5 might …

Decreased expression of long noncoding RNA GAS5 indicates a poor prognosis and promotes cell proliferation in gastric cancer

M Sun, F Jin, R Xia, R Kong, J Li, T Xu, Y Liu, E Zhang… - BMC cancer, 2014 - Springer
… was demonstrated to decrease gastric cancer cell proliferation and … GAS5 could promote
cell proliferation. Finally, we found that GAS5 could influence gastric cancer cells proliferation, …

The role of long non-coding RNA GAS5 in cancers

J Ji, X Dai, SCJ Yeung, X He - Cancer management and research, 2019 - Taylor & Francis
… The low level of GAS5 expression often elevates capacity of proliferation and predicts …
Prostate cancer is the most prevalent malignancy in male patients. Mouse xenograft models …

GAS5 long non-coding RNA in malignant pleural mesothelioma

A Renganathan, J Kresoja-Rakic, N Echeverry… - Molecular cancer, 2014 - Springer
… that GAS5 levels modify cell proliferation in vitro, and that GAS5 expression in MPM tissue
is associated with cell quiescence and podoplanin expression support a role of GAS5 in MPM …

[HTML][HTML] Decreased expression of long non-coding RNA GAS5 promotes cell proliferation, migration and invasion, and indicates a poor prognosis in ovarian cancer

J Li, H Huang, Y Li, L Li, W Hou… - Oncology …, 2016 - spandidos-publications.com
… Moreover, overexpression of GAS5 was demonstrated to suppress ovarian … cell proliferation
in vitro and in vivo. Finally, we found that GAS5 influenced ovarian cancer cell proliferation, …

The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers

C Ma, X Shi, Q Zhu, Q Li, Y Liu, Y Yao, Y Song - Tumor Biology, 2016 - Springer
… Aberrant expression of GAS5 promotes cancer cell proliferation and suppresses apoptosis
via different downstream signaling molecules in a variety of malignancy. Taken together, …

Long non‑coding RNA GAS5 inhibits cell proliferation, induces G0/G1 arrest and apoptosis, and functions as a prognostic marker in colorectal cancer

Y Yang, Z Shen, Y Yan, B Wang… - Oncology …, 2017 - spandidos-publications.com
… of GAS5 inhibited cell proliferation and survival, and induced G0/G1 cell cycle arrest and
apoptosis; however, knockdown of GAS5 expression enhanced cell proliferation, … that GAS5 is …