… advanced unresectable tumors. Typically, patients with locally advanced unresectable
pancreatic cancer … Pancreatic tumors become symptomatic at a very advanced stage; therefore, a …

… Locally advanced and metastatic pancreatic cancers are considered unresectable.
Because resection of the involved pancreas is the only treatment that offers cure, unresectable …

… by vascular invasion, locally advanced pancreatic cancer has a dismal prognosis with a 6–…
not altered the management of patients with locally advanced pancreatic cancer, a clinical …

… Nonetheless, median survival is much improved from the 8–14 months in those with
unresectable locally advanced pancreatic cancer and 4–6 months in those presenting with …

… Cancer Center, Newark, DE The treatment of patients with advanced pancreatic cancer
remains a major challenge. The outcome for this condition is extremely poor, with the median …

… patients with pancreatic cancer have advanced/… advanced/metastatic disease, and this
review will focus on recent developments in the systemic treatment of advanced pancreatic cancer…

… Despite all advances in the management of pancreatic cancer, the majority of patients
need to be treated palliatively. Survival of these patients is poor, so the main aim is to obtain a …

… LOCALLY ADVANCED LESIONS AND METASTASIS The primary goals of treatment for
advanced pancreatic cancers are palliation and improved survival. In some patients who have …

… Lack of attention to second line treatment strategy in advanced pancreatic cancer is due to
the … -line options in patients with advanced pancreatic cancer after failure of gemcitabine were …

BACKGROUND: Pancreatic cancer is the fourth leading cause of cancer-related death
worldwide. Gemcitabine is the mainstay treatment for advanced disease. However, almost all up-…