… in sepsis can control pathogen infection, excessive pyroptosis can lead to a dysregulated …
overview of the mechanisms and potential therapeutic targets underlying pyroptosis in sepsis …

… Thus, in this review, we comprehensively elaborate on the pathophysiological mechanism
and molecular signal pathways of pyroptosis and its role in the pathogenesis of autoimmune …

… of the inflammasome pathway. We discuss available pharmaceutical agents that target a
critical component of inflammasome activation, signaling leading to cellular pyroptosis, and the …

… As a type of regulated cell death (RCD) mode, pyroptosis plays an important role in several
… the pyroptosis of cancer cells. Accordingly, pyroptosis may be an important therapeutic target …

… the molecular mechanisms of NLRP3 inflammasome in pyroptosis signaling pathway, including
… Here, we focus on the molecular mechanisms of NLRP3 inflammasome in the pyroptosis …

… the mechanisms of pyroptosis and its role as a potential therapeutic target for I/R injury. …
This section discusses the role of pyroptosis in I/R injury in different organs and possible …

… how the pyroptotic signalling pathway enhances sterile inflammation in various liver
diseases, which provide potential therapeutic targets for sterile inflammatory liver diseases. …

… This study raises the hypothesis that Nek7 may be a key therapeutic target for pyroptosis.
Inhibition of pyroptosis provides a potential therapeutic avenue to cure intestinal inflammation. …

… and pathophysiological mechanisms of the pyroptosis-related inflammasomes pathway in
the … new insights for researchers regarding the development of potential therapies for DCM. …

… In terms of molecular mechanisms, the pyroptosis mechanism can be divided into two …
Pyroptosis is a potential target for the pathological mechanism and treatment of various …