A two-gene blood test for methylated DNA sensitive for colorectal cancer
SK Pedersen, RT Baker, A McEvoy, DH Murray… - PloS one, 2015 - journals.plos.org
… LCL, RTB, SKP, PLM, SM, TL are inventors on one or more patent applications covering
the methylation DNA biomarkers described in this paper. This does not alter the authors' …
the methylation DNA biomarkers described in this paper. This does not alter the authors' …
DNA methylation biomarkers for blood-based colorectal cancer screening
C Lofton-Day, F Model, T DeVos, R Tetzner… - Clinical …, 2008 - academic.oup.com
… concentration to 10 ng/PCR reaction for subsequent testing. Calibration curves were …
Universal Methylated DNA concentrations between 400 μg/L and 5 mg/L. We tested 10 ng DNA per …
Universal Methylated DNA concentrations between 400 μg/L and 5 mg/L. We tested 10 ng DNA per …
Septin 9 methylated DNA is a sensitive and specific blood test for colorectal cancer
JD Warren, W Xiong, AM Bunker, CP Vaughn… - BMC medicine, 2011 - Springer
… an improved SEPT9 blood-based CRC screening test with a … SEPT9 methylated DNA, we
demonstrate that the new test has … test is demonstrated to specifically identify CRCs from blood …
demonstrate that the new test has … test is demonstrated to specifically identify CRCs from blood …
DNA methylation as a promising landscape: A simple blood test for breast cancer prediction
G Khakpour, A Pooladi, P Izadi, M Noruzinia… - Tumor Biology, 2015 - Springer
… In the case of identifying epimarker in the peripheral blood shown in Table 1, we have two
alternatives: methylation in DNA of circulating tumor cell and WBC. Since cell-free DNA of …
alternatives: methylation in DNA of circulating tumor cell and WBC. Since cell-free DNA of …
Global methylation profiles in DNA from different blood cell types
HC Wu, L Delgado-Cruzata, JD Flom, M Kappil… - Epigenetics, 2011 - Taylor & Francis
… of differential methylation patterns in different blood cell … MN DNA methylation correlates so
closely with WBC methylation. … in the blood (70%), would be more correlated with WBC DNA …
closely with WBC methylation. … in the blood (70%), would be more correlated with WBC DNA …
From Discovery to the Clinic: The Novel DNA Methylation Biomarker mSEPT9 For The Detection of Colorectal Cancer in Blood
SR Payne - Epigenomics, 2010 - Taylor & Francis
… occult blood tests (… blood-based test would increase compliance with the current colorectal
cancer screening guidelines. In addition, a blood-based test would remove the burden of test …
cancer screening guidelines. In addition, a blood-based test would remove the burden of test …
DNA methylation profiling for a confirmatory test for blood, saliva, semen, vaginal fluid and menstrual blood
HY Lee, SE Jung, EH Lee, WI Yang, KJ Shin - Forensic Science …, 2016 - Elsevier
… DNA methylation at the 2 CpG markers was further tested by targeted bisulfite sequencing
of 461 additional samples including 49 blood, … the menstrual blood test in forensic casework. …
of 461 additional samples including 49 blood, … the menstrual blood test in forensic casework. …
Blood-based DNA methylation as biomarker for breast cancer: a systematic review
Q Tang, J Cheng, X Cao, H Surowy, B Burwinkel - Clinical epigenetics, 2016 - Springer
… of using blood-based DNA methylation marker as promising marker for BC risk stratification,
as several studies found associations between certain methylation level in blood and BC risk…
as several studies found associations between certain methylation level in blood and BC risk…
[HTML][HTML] Blood free-circulating DNA testing by highly sensitive methylation assay to diagnose colorectal neoplasias
Y Suehiro, S Hashimoto, S Higaki, I Fujii, C Suzuki… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… sample amount without DNA bisulfite treatment. We performed this study to … DNA testing by
the new methylation assay in combination with and without the fecal immunochemical test for …
the new methylation assay in combination with and without the fecal immunochemical test for …
Free-circulating methylated DNA in blood for diagnosis, staging, prognosis, and monitoring of head and neck squamous cell carcinoma patients: an observational …
A Schröck, A Leisse, L de Vos, H Gevensleben… - Clinical …, 2017 - academic.oup.com
… result, 92% (24/26) suffered from a disease progression or a second cancer and/or died
within 1 year after the first positive blood test, which is in line with the specificity of the test. …
within 1 year after the first positive blood test, which is in line with the specificity of the test. …
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