… three structural families: methyl-CpG binding domain (… to methylated DNA have been
previously determined and shown to exhibit two very different modes of methylated DNA recognition…

… These results illustrate the specific nature of mC recognition by … methylated and unmethylated
cytosine. Binding of mC by TALE repeat through the RVD NG extends the DNA recognition …

Methyl-CpG–binding proteins (MBPs) are selective readers of DNA methylation that play an
essential role in mediating cellular transcription processes in both normal and diseased cells…

… In this article, we demonstrate that the methyl-CpG dinucleotides are recognized at the MBD…
the methyl-cytosine recognition process and demonstrate that methylation enhances MBD–…

… Through several examples (Table 1), we demonstrate that ID segments outside the binding
context can influence DNA recognition. Transient contacts with the DNA binding site can …

… methylation can promote DNA-DNA recognition at methylated CpG sequences, both by
decreasing DNA … This observation fits well with current data, which indicate that methylation …

… DNA in an equivalent manner. These authors also proposed a similar model for DNA recognition
… chains within the binding face affected methyl-DNA recognition in mobility shift assays. …

… methylated DNA in a sequence-specific manner: the nucleotides surrounding the methylated
… ZBTB4 residues involved in DNA recognition. ( A ) To chelate zinc ions, GST-ZBTB4 was …

… An arginine and a glutamate interact with the methyl group. By comparison with two other …
with methylated DNA, we propose a common principle of recognition of methylated CpG by …

… methyl-CpG binding domain (MBDs). Based on the NMR structure of MBD1 complexed with
methylated DNA we analysed the recognition … methylated CpG step, the recognition mode is …