A brief review on the mechanisms of miRNA regulation

Y Cai, X Yu, S Hu, J Yu - Genomics, Proteomics and …, 2009 - academic.oup.com
… , miRNA editing, methylation and circadian clock. This mini-review summarized the current
understanding of interactions between miRNAs and … of miRNAs in various cellular processes. …

Experimental validation of miRNA targets

DE Kuhn, MM Martin, DS Feldman, AV Terry Jr… - Methods, 2008 - Elsevier
… a specific miRNA. Therefore, this review outlines several methods by which to validate miRNA
targets. Additionally, we propose that multiple criteria should be met before miRNA target …

MicroRNA (miRNA) in cancer

KB Reddy - Cancer cell international, 2015 - Springer
… representation depicting the miRNA biogenesis pathway. The primary miRNA transcript (pri-miRNA)
by RNA polymerase II or III and cleavage of the pri-miRNA by the microprocessor …

[HTML][HTML] Origins and mechanisms of miRNAs and siRNAs

RW Carthew, EJ Sontheimer - Cell, 2009 - cell.com
… Our understanding of siRNA- and miRNA-based regulation … that are under siRNA and miRNA
control in plants, and by CD … We will begin with the core aspects of the siRNA and miRNA

miRNA interplay: mechanisms and consequences in cancer

M Hill, N Tran - Disease models & mechanisms, 2021 - journals.biologists.com
miRNA:miRNA regulation: direct, indirect and global interactions, and their implications
in cancer biology. We also discuss the cell-type-specific nature of miRNA:miRNAmiRNA:miRNA

miRNAs in human cancer

TA Farazi, JI Spitzer, P Morozov… - The Journal of …, 2011 - Wiley Online Library
miRNAs frequently target hundreds of mRNAs, miRNA regulatory pathways are complex. To
provide a critical overview of miRNA … of miRNAs in cancer and then review miRNA genomic …

Evolution and Functional Diversification of MIRNA Genes

JT Cuperus, N Fahlgren, JC Carrington - The Plant Cell, 2011 - academic.oup.com
… functionality of MIRNA loci and resulting miRNAs. Additionally, some miRNAs have evolved
… of plant MIRNA genes and on the diversification of miRNA biogenesis and functionality. …

The microRNA (miRNA): overview of the RNA genes that modulate gene function

SY Ying, DC Chang, SL Lin - Molecular biotechnology, 2008 - Springer
… Primary transcripts of the miRNA genes, pri-miRNAs, are long RNA transcripts consisting
of … -like miRNA precursor. Pri-miRNAs are processed in the nucleus to pre-miRNAs by the …

miRNA nanotherapeutics for cancer

A Ganju, S Khan, BB Hafeez, SW Behrman… - Drug discovery today, 2017 - Elsevier
… Given the clinical impact of miRNAs in cancer, we review here the strategies implemented
for the delivery of tumor suppressor miRNAs or anti-miRNAs using nanotechnology-based …

[HTML][HTML] Research advances in the detection of miRNA

J Ye, M Xu, X Tian, S Cai, S Zeng - Journal of pharmaceutical analysis, 2019 - Elsevier
MiRNA functional research and clinical diagnostics have … of miRNA detection methods and
new applications. This review will provide guidelines for the development of follow-up miRNA