Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-κB ligand signaling
… marrow-derived precursor cells blocked for p38 MAPK activity and the mi/mi … p38 MAPK in
osteoclasts. In this study, we investigate whether MITF is a potential target of the p38 MAPK in …
osteoclasts. In this study, we investigate whether MITF is a potential target of the p38 MAPK in …
The underestimated role of the microphthalmia-associated transcription factor (MiTF) in normal and pathological haematopoiesis
A Oppezzo, F Rosselli - Cell & Bioscience, 2021 - Springer
… Following a stress that causes a need for new cells to replenish BM and/or circulating
blood, the p38 MAPK pathway is activated in HSCs, with p38α promoting cell cycle entry and …
blood, the p38 MAPK pathway is activated in HSCs, with p38α promoting cell cycle entry and …
Microphthalmia‐associated transcription factor in melanoma development and MAP‐kinase pathway targeted therapy
C Wellbrock, I Arozarena - Pigment cell & melanoma research, 2015 - Wiley Online Library
… of melanoma to current treatments using MAPK pathway targeting drugs, this review will
also address the role of MITF in melanoma development and BRAF/MEK inhibitor therapy. …
also address the role of MITF in melanoma development and BRAF/MEK inhibitor therapy. …
The roles of microphthalmia-associated transcription factor and pigmentation in melanoma
JJ Hsiao, DE Fisher - Archives of biochemistry and biophysics, 2014 - Elsevier
… pathway, the MAPK pathway, and the PI3K pathway. PAX3, SOX10, PGC1, LEF, and CREB
are some of the known transcription factors … by MAPK, ribosomal S6 kinase (RSK), and p38. C…
are some of the known transcription factors … by MAPK, ribosomal S6 kinase (RSK), and p38. C…
Melanocytes and the Microphthalmia Transcription Factor Network
E Steingrímsson, NG Copeland, NA Jenkins - Annu. Rev. Genet., 2004 - annualreviews.org
… of Wnt signaling, cAMP signaling may also affect Mitf function through the MAP kinase
pathway or the PI3K pathway (… Treatment of osteoclasts with Rankl results in p38 MAPK-mediated …
pathway or the PI3K pathway (… Treatment of osteoclasts with Rankl results in p38 MAPK-mediated …
Failure to target RANKL signaling through p38‐MAPK results in defective Osteoclastogenesis in the microphthalmia cloudy‐eyed mutant
HA Carey, A Bronisz, J Cabrera… - Journal of cellular …, 2016 - Wiley Online Library
… signaling pathways to induce the transcription of genes necessary for osteoclast function is
the microphthalmia-associated transcription factor, … ) family transcription factor (Hodgkinson et …
the microphthalmia-associated transcription factor, … ) family transcription factor (Hodgkinson et …
Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia
A Oppezzo, J Bourseguin, E Renaud… - The Journal of …, 2020 - Am Soc Clin Investig
… of the transcription factor microphthalmia (MiTF) through the cooperative, unscheduled
activation of several stress-signaling pathways, including the SMAD2/3, p38 MAPK, NF-κB, and …
activation of several stress-signaling pathways, including the SMAD2/3, p38 MAPK, NF-κB, and …
Epistatic connections between microphthalmia‐associated transcription factor and endothelin signaling in Waardenburg syndrome and other pigmentary disorders
K Sato‐Jin, EK Nishimura, E Akasaka… - The FASEB …, 2008 - Wiley Online Library
… of the PKC, MAPK, and cAMP pathways initiated by EDN receptor … Although MAPK is
known to link MITF to KIT signaling in … of the MAPK pathway. Here we demonstrate that EDN1 …
known to link MITF to KIT signaling in … of the MAPK pathway. Here we demonstrate that EDN1 …
C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation
… 2, p38, PI3 kinase and Akt, we show that the corresponding downstream signaling pathways
… by the activation of the Ras-Erk Map kinase pathway, treatment with a general Mek inhibitor, …
… by the activation of the Ras-Erk Map kinase pathway, treatment with a general Mek inhibitor, …
5.1 MITF (Microphthalmia-Associated Transcription Factor)
S Yokoyama, DE Fisher - Melanoma Development: Molecular …, 2017 - books.google.com
… Dev Biol 277: 155–169 ManskyKC, Sankar U, Han J, Ostrowski MC (2002) Microphthalmia
transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF…
transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF…
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