… to experimentally induced cortical spreading depression (CSD) is a key migraine-relevant …
review the synaptic alterations in the cerebral cortex of the genetic models of migraine and …

… glutamate release at cortical pyramidal cell synapses, we … cortical neurons from neonatal
WT and R192Q KI mice. Single cortical neurons grown on glial microislands form synaptic …

… cortical glutamate neurotransmitter release 8, 9. In this study, we compared the molecular …
of cortical synapse proteomes of Cacna1a R192Q KI and wild-type (WT) mice to investigate …

… However, how these alterations reverberate on cortical activity … of migraine, herein we
investigated the effects of FHM1-driven synaptic alterations in the visual cortex of awake mice. …

… for enhanced CSD susceptibility in hemiplegic migraine. Abnormal synaptic Ca 2+ homeostasis
and … Migraine is the most common neurological condition, with a prevalence of ∼15%.1 …

… expression in the cortex and hippocampus in migraine mice, especially in the hippocampal
CA1 and DG regions, where there are numerous pyramidal cells and synaptic connections. It …

… Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with
enhanced excitatory transmission in Ca V 2.1 knockin migraine mice. Neurobiol Dis 2014; 69: …

… Familial hemiplegic migraine type 1 (FHM1), a monogenic subtype of migraine with aura, is
… In FHM1 knockin mice, excitatory neurotransmission at cortical pyramidal cell synapses is …

… We propose that long-term plasticity of synaptic transmission in the cortex encodes migraine…
and reduces sensitivity to cranial pain triggers in migraine mice. Recently, we found that …

… altered cortical physiology in a genetic mouse model of familial hemiplegic migraine type 2
(… We then investigated whether synaptic activity is altered in FHM2 mice. We first recorded …