Effects of oxygen concentration on the proliferation and differentiation of mouse neural stem cells in vitro

N Horie, K So, T Moriya, N Kitagawa… - Cellular and molecular …, 2008 - Springer
… the role of pathological oxygen changes under … oxygen concentrations on mouse neural
stem cells in vitro. Methods NSCs were cultured from the ganglionic eminence of fetal ICR mice

Hypoxia enhances proliferation of mouse embryonic stem cell‐derived neural stem cells

CAV Rodrigues, MM Diogo, CL da Silva… - Biotechnology and …, 2010 - Wiley Online Library
concentrations achieved in this work are lower than the inhibitory concentrations reported
for other types of stem cells (… O2 concentrations on the ex vivo expansion of mouse ES cell-…

Lowering oxygen tension enhances the differentiation of mouse embryonic stem cells into neuronal cells

P Mondragon‐Teran, GJ Lye… - Biotechnology …, 2009 - Wiley Online Library
… of foetal and postnatal neural stem cells. These findings … nervous neural stem cells was
enhanced at reduced (5%) oxygen … that the lowering oxygen tension to physiological levels can …

Hypoxia in the regulation of neural stem cells

L De Filippis, D Delia - Cellular and Molecular Life Sciences, 2011 - Springer
… role of oxygen tension in the regulation of neural stem cells (… oxygen levels around 8%, mild
hypoxia for oxygen levels … and at 20% O 2 never appear during differentiation of mouse CNS …

The full spectrum of physiological oxygen tensions and step‐changes in oxygen tension affects the neural differentiation of mouse embryonic stem cells

P Mondragon‐Teran, JZ Baboo, C Mason… - Biotechnology …, 2011 - Wiley Online Library
oxygen concentration in … mouse neural stem cells (mNS) was at 2 and 5% O 2 . This is in
agreement with our data showing that maximum number of cells expressing the neural stem cell

Time-sensitive effects of hypoxia on differentiation of neural stem cells derived from mouse embryonic stem cells in vitro

NH Binh, H Aoki, M Takamatsu, Y Hatano… - Neurological …, 2014 - Taylor & Francis
Oxygen plays an important role in regulating the growth and differentiation state of neural stem
cells (… Although growing neural progenitor cells under low oxygen concentration depends …

[HTML][HTML] Mild hypoxia enhances proliferation and multipotency of human neural stem cells

G Santilli, G Lamorte, L Carlessi, D Ferrari… - PloS one, 2010 - journals.plos.org
… These findings raise the possibility that reduced oxygen levels occurring in neuronal disorders
… We demonstrated that oxygen concentration is also critical for the neural differentiation of …

Oxygen regulates proliferation of neural stem cells through Wnt/β-catenin signalling

L Braunschweig, AK Meyer, L Wagenführ… - Molecular and Cellular …, 2015 - Elsevier
… Reduced oxygen levels (1–5% O 2 , named herein ‘physioxia’) are beneficial for … and
stabilised active β-catenin upon physioxic cell culture in primary tissue-specific foetal mouse neural

Modulation of neuronal stem cell differentiation by hypoxia and reactive oxygen species

HLA Vieira, PM Alves, A Vercelli - Progress in neurobiology, 2011 - Elsevier
… of fetal mice exposed to different oxygen concentrations displayed the highest … oxygen
concentration promotes both events. Growing stem or neuronal progenitor cells under low oxygen

[HTML][HTML] … concentration and time window for proliferation and differentiation of neural stem cells from embryonic cerebral cortex: 5% oxygen preconditioning for 72 …

L Yuan, Y Guan, D Ma, H Du - Neural regeneration research, 2015 - journals.lww.com
… Our aim was to examine the influence of low oxygen concentration and … oxygen
concentration on the proliferation and differentiation of mouse neural stem cells in vitro Cell