… dA) adducts has already been reported with the precise chemical structures of the dG adducts
being confirmed. In the present study, we examined ES-specific dA adduct formation using …

… presence and synergistic effects of multiple adducts in close proximity. Indeed, multiple
damaged sites have been shown to exist within 24 base pairs for other types of DNA damage, (29…

… The two main analytical methods currently in use to screen for HAA–DNA adducts are the 32
… and characterize DNA adducts, and the methods applied to measure HAA–DNA adduct in …

… ]Adriamycin–DNA adducts from … DNA adducts at clinically-relevant Adriamycin concentrations.
[ 14 C]Adriamycin treatment (25 nM) resulted in 4.4 ± 1.0 adducts/10 7 bp (∼1300 adducts/…

… n ) methods can screen for DNA adducts and provide spectral information for structural …
DNA adducts. The simultaneous screening of multiple DNA adducts is the emerging field of DNA …

… important case since unrepaired DNA adducts can have wide-… of DNA adducts can inform
on exposure to a variety of DNA … Multiple methods including mass spectrometry, ELISA, and …

… containing multiple targeted bases for a carcinogen results in the formation DNA adducts at
any … induced to the ODN is increased by the potential multiple adduct formation in the ODN. …

… ) available for nucleophilic attack by the exocyclic NH 2 group at position N-2 of dG, which
in turn can result in the formation of multiple adducts (Figure 2). As for the formation of a type I …

… to DNA after metabolic activation, forming multiple DNA … multiple DNA adducts after metabolic
activation in vitro.14 Using the same method, Kawanishi et al.15 detected DNA adducts in …

… -dependent formation of multiple DNA adducts, with a … DNA adducts are formed in liver
(3.4-fold higher levels than in controls). In addition, new evidence is provided that DNA adducts …