Sirt1 inhibits oxidative stress in vascular endothelial cells
W Zhang, Q Huang, Z Zeng, J Wu… - … medicine and cellular …, 2017 - Wiley Online Library
… molecular mechanisms of Sirt1 activation and the effect of Sirt1 on endothelial protection. …
FOXO1 directly activated Sirt1 expression in vascular smooth muscle cells and HEK293 cells. …
FOXO1 directly activated Sirt1 expression in vascular smooth muscle cells and HEK293 cells. …
Endothelial SIRT1 prevents age-induced impairment of vasodilator responses by enhancing the expression and activity of soluble guanylyl cyclase in smooth muscle …
… SIRT1 is a longevity regulator … in endothelial SIRT1-mediated vasodilator responses in the
arteries of young and old mice. In particular, the contributions of nitric oxide (NO), endothelial …
arteries of young and old mice. In particular, the contributions of nitric oxide (NO), endothelial …
[HTML][HTML] Smooth muscle SIRT1 reprograms endothelial cells to suppress angiogenesis after ischemia
YQ Dou, P Kong, CL Li, HX Sun, WW Li, Y Yu, L Nie… - Theranostics, 2020 - ncbi.nlm.nih.gov
… : Vascular smooth muscle cells (… muscle SIRT1 on the functions of endothelial cells (ECs)
has not been well clarified. Here, we explored the role of smooth muscle SIRT1 in endothelial …
has not been well clarified. Here, we explored the role of smooth muscle SIRT1 in endothelial …
Endothelial SIRT1 as a target for the prevention of arterial aging: promises and challenges
MK Begum, D Konja, S Singh… - Journal of …, 2021 - journals.lww.com
… Overexpression of SIRT1 in endothelial cells does not change eNOS function but … Endothelial
SIRT1 regulates the gene expression and protein stability of sGC in smooth muscle cells …
SIRT1 regulates the gene expression and protein stability of sGC in smooth muscle cells …
Age-related loss of SirT1 expression results in dysregulated human vascular smooth muscle cell function
AM Thompson, R Wagner… - American Journal of …, 2014 - journals.physiology.org
… Specifically, in the context of cardiovascular disease, SirT1 functions to upregulate endothelial
nitric oxide synthase, reduce serum lipid levels, and decrease inflammatory cytokines (18)…
nitric oxide synthase, reduce serum lipid levels, and decrease inflammatory cytokines (18)…
Histone deacetylase SIRT1, smooth muscle cell function, and vascular diseases
F Wang, HZ Chen - Frontiers in pharmacology, 2020 - frontiersin.org
… functions of SIRT1 against VSMC senescence, and summarize the contribution of SIRT1
derived … The mutual promotion between SIRT1 and eNOS improves the endothelial function and …
derived … The mutual promotion between SIRT1 and eNOS improves the endothelial function and …
SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
I Mattagajasingh, CS Kim, A Naqvi… - Proceedings of the …, 2007 - National Acad Sciences
… demonstrate that SIRT1 plays a fundamental role in regulating endothelial NO and
endothelium-… of CR on the endothelium and vascular tone to SIRT1-mediated deacetylation of …
endothelium-… of CR on the endothelium and vascular tone to SIRT1-mediated deacetylation of …
[HTML][HTML] The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis
M Kitada, Y Ogura, D Koya - Aging (Albany NY), 2016 - ncbi.nlm.nih.gov
… that Sirt1 expression is reduced in endothelial cells obtained from … endothelial Sirt1 expression
with aging may be related to … in smooth muscle cells, endothelial cells and macrophages, …
with aging may be related to … in smooth muscle cells, endothelial cells and macrophages, …
SIRT1 in endothelial cells as a novel target for the prevention of early vascular aging
… Large arteries are rich in elastin and collagen, whereas small muscular arteries are rich in
vascular smooth muscle cells. Elastin fibers determine the mechanical strength of the blood …
vascular smooth muscle cells. Elastin fibers determine the mechanical strength of the blood …
SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells
Y Zu, L Liu, MYK Lee, C Xu, Y Liang, RY Man… - Circulation …, 2010 - Am Heart Assoc
… growth factor and the defects of TGFβ-mediated vascular smooth muscle cell recruitment.
These limited information suggest that loss of LKB1 increases angiogenic potential at least in …
These limited information suggest that loss of LKB1 increases angiogenic potential at least in …
相关搜索
- smooth muscle cells endothelial sirt1
- muscle cell function
- target for the prevention endothelial sirt1
- muscle cell hypertrophy
- dna damage muscle cell sirtuin
- human endothelial cells
- primary porcine aortic endothelial cells
- overexpression of sirt1 muscle cells
- oxidative stress in vascular endothelial cells
- regulation of sirt1 muscle cells
- impairment of vasodilator responses endothelial sirt1
- arterial aging endothelial sirt1
- soluble guanylyl cyclase endothelial sirt1
- promises and challenges endothelial sirt1
- expression and activity endothelial sirt1
- contractile differentiation muscle cells