… leukemia and KIT mutations in gastrointestinal stromal … 3 lung adenocarcinomas were found
to harbor epidermal growth factor receptor (EGFR) mutations, also a cell-surface protein with …

… Epidermal growth factor receptor (EGFR) is a transmembrane protein with cytoplasmic …
development of a subset of lung adenocarcinomas that have atypical adenomatous hyperplasia …

… The epidermal growth factor receptor (EGFR), a receptor protein … the EGFR mutation in lung
cancers. Regarding K-RAS gene, the incidence of the mutation in the lung adenocarcinomas …

… selected patients with lung adenocarcinoma carried mutations in the TK domain of the …
Given this association between EGFR protein expression and the length of the CA repeat …

… of EGFR mutation, amplification, and protein expression in … In conclusion, lung adenocarcinoma
with EGFR mutations is a … and known high response rate to EGFR TKIs. Amplification of …

… This study was designed to investigate EGFR protein expression, EGFR copy number and
EGFR mutations in lung adenocarcinomas, to explore the relationship of the three markers. …

… with EGFR mutations should be exclusively selected for EGFR TKI therapy, but provides
strong evidence that all patients with EGFR mutations with lung adenocarcinoma should be …

… oncogenicity of the resulting mutant protein, we determined that cancers harboring these …
Our finding that 1% of EGFR-mutant lung cancers harbor exon 19 insertions suggests that …

… in either the EFGR TK domain or the KRAS gene were present in 47% of lung adenocarcinomas,
no tumors contained mutations in both genes. Mutant forms of EGFR protein activate …

… The hierarchical clustering of patients according to protein abundance showed limited
correlation with the proteome landscape and the EGFR mutation type in lung adenocarcinoma (Fig…