Reactive oxygen species and the modulation of stroke

PJ Crack, JM Taylor - Free Radical Biology and Medicine, 2005 - Elsevier
… After a stroke, there is a disruption in glucose and oxygen supply to the neurons, resulting
in necrotic cell death and the formation of an infarct. Surrounding the infarct is an area termed …

Induction of reactive oxygen species in neurons by haloperidol

Y Sagara - Journal of neurochemistry, 1998 - Wiley Online Library
… HP, rat primary cortical neurons and the mouse hippocampal cell line HT-22 were … oxygen
species (ROS) and other cellular alterations caused by HP. Primary neurons and HT-22 cells

Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species

J Tanaka, K Toku, B Zhang, K Ishihara, M Sakanaka… - Glia, 1999 - Wiley Online Library
… prevented if microglial cells are cocultured with neurons (Toku et al., 1998). Furthermore,
microglial cells can prevent neuronal death caused by reactive oxygen species such as O2 and …

Reactive oxygen and nitrogen species: weapons of neuronal destruction in models of Parkinson's disease

S Przedborski, H Ischiropoulos - Antioxidants & redox signaling, 2005 - liebertpub.com
… However, in our opinion, the most compelling evidence for a role of reactive oxygen species
(ROS) and reactive nitrogen species (RNS) in the death of SNpc dopaminergic neurons in …

Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death

LJS Greenlund, TL Deckwerth, EM Johnson Jr - Neuron, 1995 - cell.com
cell death to study the mechanisms that mediate neuronal apoptosis. Cultured sympathetic
… in reactive oxygen species (ROS) that peaked at 3 hr after sympathetic neurons were …

Cadmium activates reactive oxygen species-dependent AKT/mTOR and mitochondrial apoptotic pathways in neuronal cells

Y Yan, W Yi, FF Hu, CY Jiang, YJ Zhang… - Biomedical and …, 2016 - Elsevier
… (ROS) generation in the apoptosis of neuronal cells. Methods Neuronal cells (primary rat
cerebral cortical neurons and PC12 cells) were incubated with or without Cd post-pretreatment …

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro

J Busciglio, BA Yankner - Nature, 1995 - nature.com
cell death. … oxygen species (ROS) in DS neuronal degeneration, IDS and normal cortical
cultures were treated with antioxidants from days 7 to 14 in culture. The death of DS neurons

Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate

LL Dugan, SL Sensi, LM Canzoniero… - Journal of …, 1995 - Soc Neuroscience
… neurotoxicity is partly mediated by reactive oxygen species, formed as a consequence …
neuronal mitochondria may be an important source of glutamate-induced reactive oxygen species

Reactive oxygen species in in vitro pesticide-induced neuronal cell (SH-SY5Y) cytotoxicity: Role of NFκB and caspase-3

Z Jia, HP Misra - Free Radical Biology and Medicine, 2007 - Elsevier
… the cells and increased NFκB activity in the cell nucleus. These new findings add to the growing
body of knowledge documenting that reactive oxygen speciesneurons in idiopathic PD. …

Cadmium induces reactive oxygen species generation and lipid peroxidation in cortical neurons in culture

E Lopez, C Arce, MJ Oset-Gasque, S Canadas… - Free Radical Biology …, 2006 - Elsevier
… This study presents data indicating that cadmium induces cellular death in cortical neurons
… The apoptotic death may be mediated by oxidative stress with reactive oxygen species (ROS) …