Chloroquine inhibits glutamate‐induced death of a neuronal cell line by reducing reactive oxygen species through sigma‐1 receptor

Y Hirata, H Yamamoto, MSM Atta… - Journal of …, 2011 - Wiley Online Library
… -induced cell death and reactive oxygen species production. In … -induced cell death and
reactive oxygen species production. … and induce cell death is able to rescue HT22 cells from …

Oxygen free radical injury is sufficient to cause some Alzheimer-type molecular abnormalities in human CNS neuronal cells

SM De La Monte, N Ganju, N Feroz… - Journal of …, 2000 - content.iospress.com
… transport and further production of reactive oxygen species. This study demonstrates that
8-OHdG accumulates in neuronal cells subjected to oxygen free radical injury. Therefore, the …

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

IJ Reynolds, TG Hastings - Journal of Neuroscience, 1995 - Soc Neuroscience
… across the cell bodies with processes sometimes visible (Fig. 1). Non-neuronal cells also
were labeled but, as these cells represented a relatively small proportion of the cells in our …

Determination of mitochondrial membrane potential and reactive oxygen species in live rat cortical neurons

DC Joshi, JC Bakowska - JoVE (Journal of Visualized Experiments), 2011 - jove.com
… We demonstrate application of the fluorescence indicator, TMRM, in cortical neurons to
determine … H 2 DCF-DA to assess the relative level of reactive oxygen species in cortical neurons. …

Mitochondria-derived reactive oxygen species mediate caspase-dependent and-independent neuronal deaths

MJ McManus, MP Murphy, JL Franklin - Molecular and Cellular …, 2014 - Elsevier
… mitochondria-derived reactive oxygen species (ROS) and … (NGF)-deprived sympathetic
neurons, while MitoE 2 was largely … -independent neuronal death in these cells demonstrating …

Reactive oxygen species mediate activity-dependent neuron–glia signaling in output fibers of the hippocampus

CM Atkins, JD Sweatt - Journal of Neuroscience, 1999 - Soc Neuroscience
… increase in MBP phosphorylation during neuron–glia signaling. … when reactive oxygen
species scavengers and a nitric oxide … oxygen or nitrogen species was necessary for neuron–glia …

Signaling pathways of bisphenol A–induced apoptosis in hippocampal neuronal cells: Role of calcium‐induced reactive oxygen species, mitogen‐activated protein …

S Lee, K Suk, IK Kim, IS Jang, JW Park… - Journal of …, 2008 - Wiley Online Library
… effects of BPA on neuronal cell death were investigated using hippocampal cells. The
objectives of this study were to define BPA-induced apoptotic cell death and the molecular …

Reactive oxygen species play an important role in iodoacetate-induced neurotoxicity in primary rat neuronal cultures and in differentiated PC12 cells

O Sperling, Y Bromberg, H Oelsner, E Zoref-Shani - Neuroscience letters, 2003 - Elsevier
… The role of reactive oxygen species in the pathogenesis of the … of primary rat neuronal cultures
and of differentiated PC12 cells, subjected … The injury to the cells was assessed by lactate …

Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons

SD Rao, HZ Yin, JH Weiss - Journal of Neuroscience, 2003 - Soc Neuroscience
… reactive oxygen species (ROS) generation in cultured motor neurons than in other spinal
neurons. In addition, we found that the ROS seem to be able to leave the motor neurons and …

Involvement of reactive oxygen species derived from mitochondria in neuronal injury elicited by methylmercury

Y Ishihara, M Tsuji, T Kawamoto… - Journal of Clinical …, 2016 - jstage.jst.go.jp
… When we measured cellular oxygen consumption using an oxygen-sensing dye, MitoXpress,
which indicates a high phosphorescence under hypoxic condition, SH-SY5Y cells showed …