… or other neuron cell types of a chemical stressor, in this case MPP+, inducing two distinct
waves of ROS generation that are characterized by both temporal and cellular compartment …

… Reactive oxygen species (ROS) have been extensively … in neurons ROS act as obligate
signals required for neuronal … as a redox sensor in neurons where it regulates structural plasticity…

… oxygen species (ROS) and reactive nitrogen species may be generated by inflammatory cells
through several different cellular … in apoptotic and necrotic neuronal cell death elicited by …

… To address this issue, neural cells were exposed to oxygen-glucose deprivation (OGD) and
… and 45% neuronal death in rat hippocampal and in human dopaminergic SH-SY5Y neurons, …

… is expressed at lower levels in many cell types, including cardiomyocytes, endothelial cells,
adventitial fibroblasts, neurons, and pancreatic βcells. NOX2 is activated when the regulatory …

… However, there is growing interest in the role of ROS in mediating neuronal cell death by
some excitatory neurotransmitters. Glutamate induces ROS production in neuronal cells by …

… Specifically, oxygen free radicals induce DNA sequence changes and rearrangements that
may trigger apoptotic cell death of neuronal cells. In this study, we provided the first evidence …

… oxygen species green immunostaining was present in their mitochondria, which implicates
that increased production of mitochondrial reactive oxygen species precedes neuronal death …

… related molecules in CA-exposed cells. Taken together, these results suggest that the higher
concentration of CA exerts its cytotoxic effects in neuronal cells by triggering apoptosis via a …

… oxygen species ultimately resulted in disassembly of the actin cytoskeleton. When neurons
… Therefore, we conclude that physiological levels of reactive oxygen species are critical for …