Modulation of neuronal stem cell differentiation by hypoxia and reactive oxygen species
HLA Vieira, PM Alves, A Vercelli - Progress in neurobiology, 2011 - Elsevier
… of human embryonic stem cells; the main focus of this review is to summarize the role of
oxygen during neuronal differentiation, in particular in response to oxygen level variation. …
oxygen during neuronal differentiation, in particular in response to oxygen level variation. …
Metabolic oxidation regulates embryonic stem cell differentiation
… embryonic stem cells while monitoring the effects on differentiation. … ), promoted neuronal
and cardiac differentiation. We postulate … sustained by stem cells allows them to differentiate in …
and cardiac differentiation. We postulate … sustained by stem cells allows them to differentiate in …
[HTML][HTML] Oxidative stress promotes exit from the stem cell state and spontaneous neuronal differentiation
… is a common cause of neuronal differentiation in stem cells, we next examined the effect of
GSH on atRA-mediated neuronal differentiation by co-treating NT2 cells with GSH and atRA, …
GSH on atRA-mediated neuronal differentiation by co-treating NT2 cells with GSH and atRA, …
Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells
M Yoneyama, K Kawada, Y Gotoh, T Shiba… - Neurochemistry …, 2010 - Elsevier
It is widely thought that accumulation of reactive oxygen species (ROS) causes injury to cells…
of neural stem/progenitor cells derived from the hippocampus of embryonic mice. The cells …
of neural stem/progenitor cells derived from the hippocampus of embryonic mice. The cells …
Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures
M Tsatmali, EC Walcott, H Makarenkova… - Molecular and Cellular …, 2006 - Elsevier
… differentiation of embryonic cortical progenitors. We report that rat cortical progenitors in
clonal culture produce two types of neurons … the differentiation of the two types of neurons. The …
clonal culture produce two types of neurons … the differentiation of the two types of neurons. The …
Enhanced differentiation of neural stem cells to neurons and promotion of neurite outgrowth by oxygen–glucose deprivation
Q Wang, L Yang, Y Wang - International Journal of Developmental …, 2015 - Elsevier
… , differentiation and NSC-derived neurite outgrowth. We establish the culture of adult neural
stem cells … How OGD treatments regulate NSC’s cell viability, survival and differentiation, as …
stem cells … How OGD treatments regulate NSC’s cell viability, survival and differentiation, as …
Reactive oxygen species and the neuronal fate
KAM Kennedy, SDE Sandiford, IS Skerjanc… - Cellular and Molecular …, 2012 - Springer
… cells differentiate into neurons in … neuronal differentiation [71–75], our work provided the
first demonstration that Nip can regulate neurogenesis in stem cells by regulating the cellular …
first demonstration that Nip can regulate neurogenesis in stem cells by regulating the cellular …
Roles of reactive oxygen species in the fate of stem cells
P Chaudhari, Z Ye, YY Jang - Antioxidants & redox signaling, 2014 - liebertpub.com
… Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal …
Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced …
Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced …
Mitochondrial DNA damage level determines neural stem cell differentiation fate
W Wang, Y Esbensen, D Kunke… - Journal of …, 2011 - Soc Neuroscience
… pathways determining the differentiation fate being neurons or astrocytes (… oxygen species
(ROS) levels can alter differentiation fate of mouse progenitor cells toward either neuronal …
(ROS) levels can alter differentiation fate of mouse progenitor cells toward either neuronal …
The role of oxygen in regulating neural stem cells in development and disease
DM Panchision - Journal of cellular physiology, 2009 - Wiley Online Library
… ), thereby blocking terminal differentiation of neural precursors. Increased O 2 derepresses
p53 (dotted lines), which can lead to p21 cip1 -mediated cell differentiation or apoptosis. In …
p53 (dotted lines), which can lead to p21 cip1 -mediated cell differentiation or apoptosis. In …