Recent advances in improving the bioavailability of hydrophobic/lipophilic drugs and their delivery via self-emulsifying formulations
RK Ameta, K Soni, A Bhattarai - Colloids and Interfaces, 2023 - mdpi.com
… As an oily phase, 1-oleoyl-rac-glycerol, a preliminary formulated material, was selected
because of its higher drug solubility and potent bioavailability possibilities. Tween 20, mannitol, …
because of its higher drug solubility and potent bioavailability possibilities. Tween 20, mannitol, …
Radiolabeled Cholesteryl lopanoate/Acetylated Low Density Lipoprotein as a Potential Probe for Visualization of Early Atherosclerotic Lesions in Rabbits
RE Counsell, T Scott, W Xiao, L Wang, H Liu - 1999 - deepblue.lib.umich.edu
… ester molecules in its oily core, incorporation of … loading drugs into LDL, and in our studies,
seal oil was novelly used to form microemulsion for its high efficiency of transferring the drugs …
seal oil was novelly used to form microemulsion for its high efficiency of transferring the drugs …
SYNTHESIS OF PHOSPHOLIPID CONJUGATES OF N1-(2-FURANIDYL)-N3-(2-HYDROXYETHYL)-5-FLUOROURACIL
H Chen, R Chen, P Li - Phosphorus, Sulfur, and Silicon and the …, 1997 - Taylor & Francis
… in a number of new types of phospholipid-drug conjugates. … of the trityl ether 5 obtained from
the acetylation of 4 in 80% acetic acid … The solvent was evaporated, and the oily residue was …
the acetylation of 4 in 80% acetic acid … The solvent was evaporated, and the oily residue was …
Applications of biocatalysis in fragrance chemistry: the enantiomers of α-, β-, and γ-irones
E Brenna, C Fuganti, S Serra - Chemical Society Reviews, 2008 - pubs.rsc.org
… enzyme-mediated synthesis of chiral fragrances and drugs. … acetylation of the diastereoisomeric
alcohols rac-12 and rac-… Diastereoisomer rac-17 gave an oily dinitrobenzoate ester, so …
alcohols rac-12 and rac-… Diastereoisomer rac-17 gave an oily dinitrobenzoate ester, so …
[PDF][PDF] Fungal biotransformation of xenobiotics
DG Freitag - 1995 - era.library.ualberta.ca
… For preliminary drug metabolism investigations, a viable … have demonstrated the ability to
metabolize drugs in a fashion similar to … of rac-mexiletine, rac-propranolol, and deuterated rac-…
metabolize drugs in a fashion similar to … of rac-mexiletine, rac-propranolol, and deuterated rac-…
Evaluation of 2, 2′-anhydro-1-(3′-O-acetyl-β-D-arabinofuranosyl)-5-iodocytosine hydrochloride and related compounds as antineoplastic and antiviral agents
YH Itoh, MY Chu, PK Chang, HS Allaudeen… - Chemico-Biological …, 1981 - Elsevier
… After removal of the solvent in vacuo, the oily residue was … saline (PBS) in place of drug.
The final number of cells was … /mouse) and drug therapy was initiated 24 h later. A solution of …
The final number of cells was … /mouse) and drug therapy was initiated 24 h later. A solution of …
Comparative study between high-pressure homogenisation and Shirasu porous glass membrane technique in sildenafil base-loaded solid SNEDDS: effects on …
… original drug of the currently marketed oral administration dosage form, Viagra® is a drug …
and round form in various size distribution as if oily ingredients were absorbed on the pores of …
and round form in various size distribution as if oily ingredients were absorbed on the pores of …
[HTML][HTML] Mannosylated preactivated hyaluronic acid-based nanostructures for bacterial infection treatment
… The shake flask method was used to determine the drug solubility in the different excipients
(oil, … In 72 h, 85 % of the drug was released in a sustained manner, and the entrapment …
(oil, … In 72 h, 85 % of the drug was released in a sustained manner, and the entrapment …
An aptamer based surface plasmon resonance biosensor for the detection of ochratoxin A in wine and peanut oil
Z Zhu, M Feng, L Zuo, Z Zhu, F Wang, L Chen… - Biosensors and …, 2015 - Elsevier
… methods were developed for the separation of OTA from complex components existing in
wine and peanut oil samples and we have successful implemented the detection of oily …
wine and peanut oil samples and we have successful implemented the detection of oily …
Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density
VCF Mosqueira, P Legrand, JL Morgat, M Vert… - Pharmaceutical …, 2001 - Springer
… The rapid uptake of colloidal drug carrier systems by the … chains to the hydrophobic
poly(rac-lactide) polymer allowed … from polymer without an oily core and liposomes formed from …
poly(rac-lactide) polymer allowed … from polymer without an oily core and liposomes formed from …