… During the first 8 years after surgical resection, 80% of patient deaths are preceded by a
tumor recurrence. On an individual patient basis, in this analysis, 80% of patients who …

Purpose Progression-free survival (PFS) has previously been established as a surrogate for
overall survival (OS) for first-line metastatic colorectal cancer (mCRC). Because mCRC …

… control and EFS were strongly correlated with those on overall survival (R=0·94 and 0·98, …
overall survival were stronger than those between locoregional control and overall survival (…

… progression-free survival and overall survival in patients with BRAF V600 -mutant melanoma,
although the degree of treatment benefit varied. Studies of small groups of patients treated …

… endpoints and overall survival at individual and trial levels. … DFS and overall survival were
very good at the individual level … and overall survival were very good at the individual level (ρ 2 …

… to determine the pooled overall treatment effect on OS of … patients with newly diagnosed
EGFR-mutated advanced NSCLC using individual patient data from RCTs with updated survival …

… The IPD MA (5), which analyzed 987 patients with SCLC in complete remission, showed
that PCI improved overall survival with an HR of 0.84 (95 percent confidence interval [CI], 0.73–…

… To our knowledge, this is the first prediction model for overall survival of patients with
stage III NSCLC treated with (chemo) radiation therapy. The performance of the model in the …

… Increased long-term survival presents additional challenges for determining … patients’ lives
through clinical trials, commonly known as the gold standard endpoint of overall survival (OS). …

… We noted a predicted median overall survival time of 20·17 months (95% CI 12·42–not …
predicted overall survival time increased to 65·38 months (56·02–71·52) when a person within the …