MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a …
… However, MGMT methylation status does not always … MGMT promoter methylation improves
response to alkylating therapy is still unknown. MGMT promoter methylation status testing is …
response to alkylating therapy is still unknown. MGMT promoter methylation status testing is …
[HTML][HTML] Comprehensive analysis of MGMT promoter methylation: correlation with MGMT expression and clinical response in GBM
… ) test based on the 3R classification and show that this test is both feasible in the clinical setting
and predictive of progression free survival … of a test based on this promoter-wide analysis …
and predictive of progression free survival … of a test based on this promoter-wide analysis …
Prognostic value of test (s) for O6‐methylguanine–DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma …
A McAleenan, C Kelly, F Spiga… - Cochrane Database …, 2021 - cochranelibrary.com
… In this Cochrane Review, we aimed to assess which way of measuring methylation of the
MGMT promoter best predicts survival for people with glioblastoma who are treated with …
MGMT promoter best predicts survival for people with glioblastoma who are treated with …
MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges
A Mansouri, LD Hachem, S Mansouri, F Nassiri… - Neuro …, 2019 - academic.oup.com
… Hegi et al observed that even among unmethylated patients treated with radiation and TMZ,
progression-free survival (PFS) was significantly improved, while increase in overall survival …
progression-free survival (PFS) was significantly improved, while increase in overall survival …
The utilization of MGMT promoter methylation testing in United States hospitals for glioblastoma and its impact on prognosis
A Lee, I Youssef, VW Osborn, J Safdieh… - Journal of Clinical …, 2018 - Elsevier
… overall survival (OS) by coding status of MGMT promoter … patterns of MGMT promoter
methylation testing using the … ) to analyze completeness of coding for MGMT as well as to compare …
methylation testing using the … ) to analyze completeness of coding for MGMT as well as to compare …
MGMT promoter methylation in malignant gliomas: ready for personalized medicine?
M Weller, R Stupp, G Reifenberger… - Nature Reviews …, 2010 - nature.com
… and overall survival in WHO grade III anaplastic glioma patients with MGMT promoter
methylation, … In other words, the test needs to predict overall dense promoter methylation that is …
methylation, … In other words, the test needs to predict overall dense promoter methylation that is …
[HTML][HTML] Prognostic Value of Three Different Methods of MGMT Promoter Methylation Analysis in a Prospective Trial on Newly Diagnosed Glioblastoma
A Christians, C Hartmann, A Benner, J Meyer… - PloS one, 2012 - journals.plos.org
… prediction of progression-free survival (PFS). The MGMT promoter methylation status was
… -rank statistics to test for cut-points in the continuous CpG methylation data obtained by PSQ …
… -rank statistics to test for cut-points in the continuous CpG methylation data obtained by PSQ …
MGMT Promoter Methylation Predicts Overall Survival after Chemotherapy for 1p/19q-Codeleted Gliomas
CJ Kinslow, AI Rae, K Taparra, P Kumar… - Clinical Cancer …, 2023 - AACR
… , our study highlights an opportunity to increase MGMT testing nationwide for oligodendroglial
tumors. However, widespread adoption will likely not be realized until further guidance is …
tumors. However, widespread adoption will likely not be realized until further guidance is …
MGMT Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide: A Pooled Analysis of Four Clinical …
ME Hegi, E Genbrugge, T Gorlia, R Stupp… - Clinical Cancer …, 2019 - AACR
… the extent of MGMT promoter methylation and overall survival (OS). … MGMT promoter
methylation data was obtained from four trials for newly diagnosed GBM, with central MGMT testing …
methylation data was obtained from four trials for newly diagnosed GBM, with central MGMT testing …
[HTML][HTML] The prognostic value of MGMT promoter status by pyrosequencing assay for glioblastoma patients' survival: a meta-analysis
H Zhao, S Wang, C Song, Y Zha, L Li - World journal of surgical oncology, 2016 - Springer
… ) for overall survival (OS) and the progression-free survival (… of MGMT promoter methylation
among GBM was assessed. … , direct testing status of MGMT promoter methylation might be …
among GBM was assessed. … , direct testing status of MGMT promoter methylation might be …
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