Sources of reactive oxygen species production in excitotoxin-stimulated cerebellar granule cells

AA Boldyrev, DO Carpenter, MJ Huentelman… - Biochemical and …, 1999 - Elsevier
… intracellular ROS production for cells pre-loaded with DCFH-DA (15). In the present studies,
DCF fluorescence was used to measure ROS production in cerebellar granule cells by flow …

Detection of reactive oxygen species in primary cultures of cerebellar granule cells

A Atlante, S Passarella - Brain Research Protocols, 1999 - Elsevier
oxygen, respectively. Both of them were used to assess the formation of … oxygen species
in cerebellar granule cells exposed to glutamate: both superoxide anion and singlet oxygen

Oxygen-induced regulation of Na/K ATPase in cerebellar granule cells

IY Petrushanko, NB Bogdanov, N Lapina… - The Journal of general …, 2007 - rupress.org
… a cosubstrate for NO production. Alternatively, reactive oxygen species produced from O 2
… − and NO 2 − production reflecting NOS activity in cerebellar granule cells peaks at pO 2 of 3…

Production of Reactive Oxygen Species and Release of l‐Glutamate During Superoxide Anion‐Induced Cell Death of Cerebellar Granule Neurons

T Satoh, T Numakawa, Y Abiru… - Journal of …, 1998 - Wiley Online Library
… + XO triggered cell death associated with increased production of ROS in cerebellar granule
… by NO donors in cerebellar granule cells require NMDA receptor activation. J. Neurochem. …

Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons

A Valencia, J Morán - Journal of neuroscience research, 2001 - Wiley Online Library
oxygen species (ROS) occurred at three different times, 10 min, 30 min and 3–4 hr but only
those ROS produced after 3–4 hr are involved in the process of cellcerebellar granule cells (…

Different sources of reactive oxygen species contribute to low potassium-induced apoptosis in cerebellar granule cells

A Bobba, A Atlante… - … journal of molecular …, 2008 - spandidos-publications.com
… An early increase in ROS production is characteristic of cerebellar granule cells undergoing
apoptosis in the presence of 5 mM KCl. However, the sources of this increase have not been …

… /necrosis transition in cerebellar granule cells depends on the mutual relationship of the antioxidant and the proteolytic systems which regulate ROS production and …

A Atlante, A Bobba, P Calissano… - Journal of …, 2003 - Wiley Online Library
… We investigate the death route induced by potassium depletion in cerebellar granule cells
between the cell antioxidant and proteolytic system. To achieve this, we incubated cells in the …

Kaempferol blocks oxidative stress in cerebellar granule cells and reveals a key role for reactive oxygen species production at the plasma membrane in the …

AK Samhan-Arias, FJ Martı́n-Romero… - Free Radical Biology …, 2004 - Elsevier
… Reactive oxygen species (ROS) produced at the early phase … that most cell-damaging ROS
are produced by mitochondria. … produced 3–4 h after induction of cerebellar granule cell (…

Glutamate neurotoxicity in rat cerebellar granule cells: a major role for xanthine oxidase in oxygen radical formation

A Atlante, S Gagliardi, GM Minervini… - Journal of …, 1997 - Wiley Online Library
… With the procedure used in the present study, O2~production is a!ready detectable almost
immediately after addition of glutamate, and further release can be followed in the same …

Oxidative stress, mitochondrial function, and acute glutamate excitotoxicity in cultured cerebellar granule cells

RF Castilho, MW Ward… - Journal of …, 1999 - Wiley Online Library
… In this article we investigate the contribution played by ROS generation in the phenomenon
of granule cell DCD. It is found that the glutamate-dependent component of ROS production