… neuronal death caused by oxygen toxicity requires protein and RNA synthesis. Both agents
effectively prevented neuronal cell … that PC12 cells exposed to a high-oxygen atmosphere …

… investigate the neuronal cell damage induced by oxygen toxicity and its … cells in various
oxygen atmospheres and observed cell death in a high oxygen atmosphere (over 50% oxygen). …

… Under these conditions we found that both superoxide anion and singlet oxygen lead to
cell death with apoptotic characteristics, whereas hydrogen peroxide induces a necrosis-like …

… toxic and that the main effector of this type of cell death is H 2 O 2 . However, it is not clear
which ROS is the main effector of oxygen toxicity… 2 O 2 are effectors of neuronal cell death. The …

… may trigger the onset of neuronal apoptosis in AD. Aβ might also induce the neuronal cell
death directly by activating the pro-apoptotic components (Fig. 4). However, further studies are …

… ultimate neuronal death. In this study, we focused on the neuronal cell death induced by
oxygen toxicity, … aspects of oxygen-induced neuronal death and the restorative mechanisms of …

… of apoptosis induced by oxidative stress in neuronal cells. … PC12 cells were much more
resistant to oxygen toxicity than those … indicated that oxygen-induced apoptosis in PC12 cells is …

… a disturbance of mitochondrial function and eventually neuronal cell death. To this end, we
… oxygen intermediates (ROI). Since GSH depletion has been shown to precede apoptotic cell …

… induce apoptosis of the neuronal cells through … of apoptosis was visualized by Hoechst
33258 staining under a fluorescence microscope. The arrows indicate apoptotic neuronal cells …

… oxygen levels can trigger apoptotic neurodegeneration in the brains of infant rodents.
Vulnerability to oxygen … , is a powerful trigger for apoptotic neuronal death in the developing brain. …