BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
… oncogenic activation of the mutated BRAF kinase (33, 43). A few other … BRAF mutants are
only rarely found in thyroid cancer, such as the BRAF K601E (44), AKAP9-BRAF (45), BRAF

Prognostic utility of BRAF mutation in papillary thyroid cancer

M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
Papillary thyroid cancer (PTC) is a common endocrine malignancy that frequently harbors
the oncogenic T1799A BRAF mutation. As a novel prognostic molecular marker, this mutation

BRAF mutation in papillary thyroid carcinoma

Y Cohen, M Xing, E Mambo, Z Guo… - … the National Cancer …, 2003 - academic.oup.com
… neck cancers but not in bladder, cervical, or prostate cancers. Our data suggest that activating
BRAF mutations may be an important event in the development of papillary thyroid cancer. …

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
BRAF V600E–negative and BRAF V600E–positive groups for all patients and for patients with
conventional papillary thyroid cancer (PTC… of the Interaction of BRAF V600E Mutation With …

BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications

KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
… the most rapidly increasing cancer among women and the … thyroid cancers are classified
into papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer

[PDF][PDF] BRAF (V600E) mutation and the biology of papillary thyroid cancer

F Frasca, C Nucera, G Pellegriti, P Gangemi… - … -related cancer, 2008 - academia.edu
… Investigation of BRAF mutation in a series of papillary thyroid carcinoma and matched-lymph
node metastasis reveals a new mutation in metastasis. Clinical Endocrinology 62 509–511. …

Association Between BRAF V600E Mutation and Recurrence of Papillary Thyroid Cancer

M Xing, AS Alzahrani, KA Carson, YK Shong… - Journal of clinical …, 2015 - ascopubs.org
… Joint Committee on Cancer staging system. Genomic … BRAF gene to identify BRAF V600E
mutation, as described in our previously published studies. In all cases, BRAF V600E mutation

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
… shown that this BRAF mutation occurs in papillary thyroid cancer (PTC) … BRAF mutation
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid

BRAF mutations are associated with some histological types of papillary thyroid carcinoma

V Trovisco, I Vieira de Castro, P Soares… - The Journal of …, 2004 - Wiley Online Library
… The hot-spot mutation BRAF V599E is frequently detected in PTC (36–… thyroid lesions. In
order to unravel whether there is any association between the occurrence of the BRAF mutation

BRAFV600E Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid Cancer

S Kim, KE Lee, JP Myong, J Park, YK Jeon… - World journal of …, 2012 - Springer
… section of thyroid tumor. We analyzed the prevalence of the BRAF V600E mutation and …
Data regarding age at diagnosis, gender, tumor size, multifocality, extrathyroidal extension, …