BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
… of thyroid cancer are papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and
anaplastic thyroid cancer (… of this mutation, such as thyroid cancer (13), the focus of this review. …

Prognostic utility of BRAF mutation in papillary thyroid cancer

M Xing - Molecular and cellular endocrinology, 2010 - Elsevier
… The vast majority of thyroid cancers originate from follicular epithelial cells, which are … as
papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), and anaplastic thyroid cancer (…

BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis

RP Tufano, GV Teixeira, J Bishop, KA Carson, M Xing - Medicine, 2012 - journals.lww.com
… ) mutation in exon 15 of the BRAF gene has been noted to be a putative prognostic marker
of the most prevalent form of thyroid cancer, papillary thyroid cancer (… of BRAF mutation with …

[PDF][PDF] BRAF (V600E) mutation and the biology of papillary thyroid cancer

F Frasca, C Nucera, G Pellegriti, P Gangemi… - … -related cancer, 2008 - academia.edu
BRAF (V600E) mutation is the most frequent genetic alteration in papillary thyroid carcinomas
(PTCs) that are 80–90% of all thyroid cancers. We evaluated the relationship between …

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer

M Xing, WH Westra, RP Tufano, Y Cohen… - The Journal of …, 2005 - academic.oup.com
… shown that this BRAF mutation occurs in papillary thyroid cancer (PTC) with a … mutation
occurs exclusively in PTC and PTC-derived anaplastic thyroid cancers but not in normal thyroid

The association of the BRAFV600E mutation with prognostic factors and poor clinical outcome in papillary thyroid cancer: A meta‐analysis

TH Kim, YJ Park, JA Lim, HY Ahn, EK Lee, YJ Lee… - Cancer, 2012 - Wiley Online Library
… The majority of the incidences of thyroid cancer are papillary thyroid cancer (PTC), which
accounts for approximately 85%.3 Although most PTC patients have excellent overall survival, …

BRAF mutation in papillary thyroid carcinoma

Y Cohen, M Xing, E Mambo, Z Guo… - … the National Cancer …, 2003 - academic.oup.com
… BRAF mutations may be an important event in the development of papillary thyroid cancer. …
Our observation of a high frequency of BRAF-activating mutations in papillary thyroid

Papillary thyroid cancer prognosis: An evolving field

S Ulisse, E Baldini, A Lauro, D Pironi, D Tripodi, E Lori… - Cancers, 2021 - mdpi.com
… Putative cancer driver mutations have been identified in more than 98% of PTC, and a new
PTC classification into molecular subtypes has been proposed in order to resolve clinical …

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
… BRAF V600E is a prominent oncogene in papillary thyroid cancer (PTC), but its role in
PTC-… of the BRAF V600E mutation was significantly associated with increased cancer-related …

Association Between BRAF V600E Mutation and Recurrence of Papillary Thyroid Cancer

M Xing, AS Alzahrani, KA Carson, YK Shong… - Journal of clinical …, 2015 - ascopubs.org
… V600E mutation for the recurrence of papillary thyroid cancer (PTC). … mutation status on
disease recurrence–free probability in patients with various types of papillary thyroid cancer (PTC…