Clinical Responses to Vemurafenib in Patients with Metastatic Papillary Thyroid Cancer Harboring BRAFV600E Mutation

KB Kim, ME Cabanillas, AJ Lazar, MD Williams… - Thyroid, 2013 - liebertpub.com
… Clin Cancer Res 15:485–491. Crossref, Medline, Google … of BRAF mutation in metastasized
papillary thyroid cancer in … of BRAF mutation in metastasized papillary thyroid cancer in …

[HTML][HTML] BRAF V600E mutation in prognostication of papillary thyroid cancer (PTC) recurrence

A Czarniecka, M Oczko-Wojciechowska… - Gland …, 2016 - ncbi.nlm.nih.gov
… The beginning of 2000 marked the interest in BRAF gene mutation in thyroid cancer. At that
time studies on the role of the mutation in other cancers (eg, melanoma, colon cancer) had …

Impact of mutation density and heterogeneity on papillary thyroid cancer clinical features and remission probability

C Colombo, M Muzza, MC Proverbio, D Tosi… - Thyroid, 2019 - liebertpub.com
… a large series of 208 papillary thyroid cancers (PTC) followed … genetic alterations, including
point mutations and fusions. … V600E and TERT promoter mutations being the most frequent …

A six-genotype genetic prognostic model for papillary thyroid cancer

X Shen, R Liu, M Xing - Endocrine-related cancer, 2017 - erc.bioscientifica.com
… promoter mutations in papillary thyroid cancer (PTC) has been recently established, but the
role of RAS mutation in this genetic interplay remains to be established. Using The Cancer

BRAF V600E and TERT Promoter Mutations Cooperatively Identify the Most Aggressive Papillary Thyroid Cancer With Highest Recurrence

M Xing, R Liu, X Liu, AK Murugan, G Zhu… - Journal of clinical …, 2014 - ascopubs.org
thyroid cancer, such as anaplastic thyroid cancer and poorly differentiated thyroid cancer, as
well as BRAF V600E mutation… V600E and TERT C228T mutations may cooperatively form a …

BRAF V600E mutation and papillary thyroid cancer

M Xing - Jama, 2013 - jamanetwork.com
mutation is not a determinant of the metastatic potential of PTC. Papillary thyroid cancers are
… determine the most appropriate use of the BRAF mutation as a clinical marker, whereas we …

p53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancer

DG McFadden, A Vernon… - Proceedings of the …, 2014 - National Acad Sciences
… We generated a thyroid-specific CreER transgenic mouse … )-mutant papillary thyroid cancer
to anaplastic thyroid cancer (ATC)… lacking mouse model of BRAF-mutant ATC and adds to the …

BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications

KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
thyroid cancers are classified into papillary thyroid cancer (PTC), follicular thyroid cancer (FTC),
and anaplastic thyroid cancer (ATC)… for 85–90% of all thyroid malignancies.Differentiated …

Increase in Papillary Thyroid Cancer Incidence Is Accompanied by Changes in the Frequency of the BRAFV600E Mutation: A Single-Institution Study

A Kowalska, A Walczyk, A Kowalik, I Pałyga, T Trybek… - Thyroid, 2016 - liebertpub.com
… Background: Thyroid cancer (TC) has one of the fastest increasing incidences worldwide
and primarily involves papillary thyroid cancer (PTC). The BRAFV600E mutation is the most …

Effects of Coexistent BRAFV600E and TERT Promoter Mutations on Poor Clinical Outcomes in Papillary Thyroid Cancer: A Meta-Analysis

S Moon, YS Song, YA Kim, JA Lim, SW Cho, JH Moon… - Thyroid, 2017 - liebertpub.com
… marker for thyroid cancer, and a synergistic association with the BRAF V600E mutation has
… The aim of this study was to verify the role of this genetic duet in papillary thyroid cancer (…