Ambient particulate matter induces interleukin-8 expression through an alternative NF-κB (nuclear factor-kappa B) mechanism in human airway epithelial cells

R Silbajoris, AR Osornio-Vargas… - Environmental …, 2011 - ehp.niehs.nih.gov
… To characterize relevant mechanisms that lead to inflammatory responses to PM inhalation,
we examined the activation of signaling events involved in IL-8 expression in a model of …

[HTML][HTML] Exposure to ambient particulate matter induced COPD in a rat model and a description of the underlying mechanism

F He, B Liao, J Pu, C Li, M Zheng, L Huang, Y Zhou… - Scientific reports, 2017 - nature.com
… These cells can also serve as effectors to initiate and orchestrate immune and inflammatory
inflammatory cells in the lungs of the experimental rats, we characterized the inflammatory

Effect of particulate matter air pollution on cardiovascular oxidative stress pathways

X Rao, J Zhong, RD Brook… - Antioxidants & redox …, 2018 - liebertpub.com
… of particulate matter (PM) air pollution-mediated inflammation and … of the role of redox
mechanisms where redox-active mediators, … We address mechanisms surrounding pulmonary …

[HTML][HTML] Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin

YS Ryu, KA Kang, MJ Piao, MJ Ahn, JM Yi, YM Hyun… - Redox biology, 2019 - Elsevier
Particulate matter (PM) increases levels of pro-inflammatory … regulatory mechanisms
underlying cellular inflammation … skin keratinocytes produced various inflammatory cytokines, …

Respiratory health effects of diesel particulate matter

ZD Ristovski, B Miljevic, NC Surawski… - …, 2012 - Wiley Online Library
inflammation mediated via oxidative stress is the mechanism by which DPM may exert toxicity.
In this section of the review, the inflammatory … A mechanism was proposed in this review …

The effects of ambient particulate matter on human alveolar macrophage oxidative and inflammatory responses

K Sawyer, S Mundandhara, AJ Ghio… - Journal of Toxicology …, 2009 - Taylor & Francis
… This study also explored the broad mechanisms that may … and inflammation may be involved,
markers of oxidative stress as well as the production and release of several inflammatory

[HTML][HTML] Particulate matter impairs immune system function by up-regulating inflammatory pathways and decreasing pathogen response gene expression

D Marín-Palma, GJ Fernandez, J Ruiz-Saenz… - Scientific Reports, 2023 - nature.com
… The molecular mechanisms and changes in gene … mononuclear cells after exposure to
coarse particulate matter (PM 10 ). … recruitment suggest mechanisms for inflammation upon PM …

Ambient fine particulate matter induces inflammatory responses of vascular endothelial cells through activating TLR-mediated pathway

Y Le, X Hu, J Zhu, C Wang… - … and Industrial Health, 2019 - journals.sagepub.com
… The mechanisms of PM 2.5 -induced inflammatory reaction of vascular endothelial cells
have still remained elusive. A few studies showed that the exposure to air particles stimulated …

Inhaled Particulate Matter Causes Expression of Nuclear Factor (NF)- κ B–Related Genes and Oxidant-Dependent NF- κ B Activation In Vitro

A Shukla, C Timblin, K BeruBe, T Gordon… - American journal of …, 2000 - atsjournals.org
… concerning the mechanisms of inflammation and toxicity by components of inhaled particulate
matter (… Studies here are the first to show NF- κ B–related inflammatory and cytokine gene …

Fine particulate matter and sulfur dioxide coexposures induce rat lung pathological injury and inflammatory responses via TLR4/p38/NF-κB pathway

R Li, L Zhao, J Tong, Y Yan… - International journal of …, 2017 - journals.sagepub.com
… role in the initiation and development of lung inflammation, while they probably constitute
a … inflammatory mechanism of coexposure of SO 2 and PM 2.5 along with pro-inflammatory