The pathogenesis of sepsis and potential therapeutic targets
M Huang, S Cai, J Su - International journal of molecular sciences, 2019 - mdpi.com
… diagnosis, treatment, and management of patients with sepsis. … pathogenesis and the target
of clinical diagnosis of sepsis, with the goal of enhancing the current understanding of sepsis…
of clinical diagnosis of sepsis, with the goal of enhancing the current understanding of sepsis…
The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL van de Veerdonk… - Nature Reviews …, 2017 - nature.com
… after the induction of sepsis, which suggests a … potential therapeutic target in sepsis 42 .
Monocyte PDL1 expression is an independent predictor of 28-day mortality in patients with septic …
Monocyte PDL1 expression is an independent predictor of 28-day mortality in patients with septic …
Emerging therapeutic targets for sepsis
EW Tindal, BE Armstead, SF Monaghan… - … on therapeutic targets, 2021 - Taylor & Francis
… In summary, while the innate immune system is rich in potential therapeutic targets and
remains a promising area of research, as has been demonstrated by the study of cytokines in this …
remains a promising area of research, as has been demonstrated by the study of cytokines in this …
Therapeutic targets in sepsis: past, present, and future
EJ Seeley, GR Bernard - Clinics in Chest Medicine, 2016 - chestmed.theclinics.com
… evolution of sepsis therapy (Table 1) and identifies possible causes for why rational therapies
failed in human trials. In addition, this article examines potential future sepsis targets and …
failed in human trials. In addition, this article examines potential future sepsis targets and …
Novel therapeutic targets for sepsis: regulation of exaggerated inflammatory responses
… activation appears to be a potential therapeutic candidate for sepsis. Stem Cells in Sepsis
… understanding, and may shed light on novel therapeutic targets for the treatment of sepsis. …
… understanding, and may shed light on novel therapeutic targets for the treatment of sepsis. …
Cytokines in sepsis: potent immunoregulators and potential therapeutic targets—an updated view
W Schulte, J Bernhagen, R Bucala - Mediators of inflammation, 2013 - Wiley Online Library
… actions in recent years, a number of therapeutic strategies targeting cytokines and other …
septic patients. Their current role in the treatment of sepsis is discussed later in this review. …
septic patients. Their current role in the treatment of sepsis is discussed later in this review. …
Pathogenetic aspects of sepsis and possible targets for adjunctive therapy
O Rigato, E Silva, EG Kallas… - Current Drug Targets …, 2001 - ingentaconnect.com
… still die of sepsis. Thus, strategies focusing on further therapy targets are an important area
of interest for basic and clinical research. Although such adjunctive sepsis therapy has failed …
of interest for basic and clinical research. Although such adjunctive sepsis therapy has failed …
Therapeutic intervention and targets for sepsis
TW Rice, GR Bernard - Annu. Rev. Med., 2005 - annualreviews.org
… into additional therapeutic agents directed against novel targets. Following a review of
recent advances in sepsis treatment, we briefly discuss a few of the new, promising therapeutic …
recent advances in sepsis treatment, we briefly discuss a few of the new, promising therapeutic …
Dendritic cells in sepsis: potential immunoregulatory cells with therapeutic potential
V Kumar - Molecular immunology, 2018 - Elsevier
… Still, we are struggling for the identification of a specific therapeutic target for the management
of sepsis in the clinics and intensive care units (ICUs) around the world. For example, data …
of sepsis in the clinics and intensive care units (ICUs) around the world. For example, data …
An ongoing search for potential targets and therapies for lethal sepsis
… that might contribute to the pathogenesis of lethal sepsis. To identify such mediators, we …
clinically feasible therapeutic targets (such as IL-3) and medications for human sepsis [131]. …
clinically feasible therapeutic targets (such as IL-3) and medications for human sepsis [131]. …
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